Cutaneous leishmaniasis: rifampicin, cryotherapy and combined therapy: a comparative study

Cutaneous leishmaniasis is a speeific granuloma of the skin affecting millions of people throughout the world. Treatment has been controversial. As the disease evolves chronically. Usually with slow self- healing but can become nonhealing. Diffuse, disseminating or relapsing Evaluating the results of an oral drug [Rifampicin]. A surgical procedure [cryotherapy] and their combined effect. Showed that 53.3% of cases were cured by Rifampicin. 57.1% of cases by cryotherapy and 100% of cases by combined therapy. Also combined therapy showed a significantly shorter duration of therapy than either alone. Thus combined therapy can be considered safe and effective for treatment of cutaneous leishmaniasis