efficacy of cefuroxime in the treatment of bacterial meningitis in infants and children

Fortyeight cases of proven bacterial meningitis due to one of six causative organisms were treated with cefuroxime. Cefuroxime was clinically and bacteriologically effective in 40 cases. Failure of response was due to one of several factors infection with resistant organism e.g. staph. aureus resistant to the drug, bad general condition, fulminating forms of the disease and rapid death with no sufficient duration of therapy. Cefurozime, on the whole could be considered as the drug of choice for the treatment of meningitis due to Str. pneumoniae, N meningitidis, Staph. aureus, salmonella and H. influenzae