Synthesis of some new benzimidazole derivatives with evaluation of their antimicrobial activity

A series of N1-p-[2-benzimidazoylamino] benzoyl] N2-arylidene hydrazine [3a-e], pyrazolone 4 pyrazole 5, carbothioamide 6a-c, 1,3,4-thiadiazol 7 and 1,3,4-triazoles 8 were prepared. Some of the new compounds showed considerable antimicrobial activity against Gram +ve, Gram -ve bacteria, yeast and fungi

Synthesis of some novel benzimidazole derivatives as antimicrobial agents

Synthesis of 2-[p-[5-aryl-1-[H or phenyl]-delta2 pyrazolin-3-yl] anilino] benzimidazoles [4a, b], 2-[p-aryl-2-isoxazolin-3-yl] anilino] benzimidazole [5], 2-[p-[6-aryl-2-[oxo or thioxo]-1,2,5,6- tetrahydropyrimidin-4-yl] anilino] benzimidazoles [6a,b] and 2-[p- sulfamoylanilino] benzimidazoles [7a-g] were synthesized. The new compounds showed inhibitory effect against the growth of Gram +ve, Gram -ve bacteria, yeast and fungi