Evaluating the correlation between histopathological patterns of oral squamous cell carcinoma, age and site

The objective of this study was to provide a baseline data on the pattern of oral squamous cell carcinoma in Karachi and to find a correlation between the clinical patterns of oral squamous cell carcinoma with age and site. The retrospective cross sectional study was conducted. The patients of oral squamous cell carcinoma were examined from January 2007- December 2010 at oral maxillofacial department, Darul Sehat Hospital Karachi. All retrievable case files were obtained and necessary data were extracted regarding age, gender, site and histological type. All cases were clinically examined and provisionally diagnosed. Biopsy was taken from the lesions and tissues were fixed in 10% buffered formalin and submitted to histopathologic department for histological confirmation. 62% of males and 38% females were diagnosed with squamous cell carcinoma. 30% were observed in age group of 41-50 years old. 45% of squamous cell carcinoma were on buccal mucosa. Correlation between the 2 variables i.e., site to histological type and age to histological type was found to be statistically significant. Level of significance was set at 0.05. However, the strength of association was weak between the selected variables. OSCC was most common of all oral malignancies of which most were in the older age group. Serious thought should be given to prevention and early detection

Histopathological patterns of oral squamous cell carcinoma

The objective of this study was to provide a baseline data on the pattern of oral squamous cell carcinoma in Karachi. The retrospective cross sectional study was conducted. The patients of oral squamous cell carcinoma were examined from January 2007- December 2010 at oral maxillofacial department, Darul Sehat Hospital Karachi. All retrievable case files were obtained and necessary data were extracted regarding age, gender, site and histological type. All cases were clinically examined and provisionally diagnosed. Biopsy was taken from the lesions and tissues were fixed in 10% buffered formalin and submitted to histopathologic department for histological confirmation. 62% of males and 38% females were diagnosed with squamous cell carcinoma. 30% were observed in age group of 41-50 years old. 45% of squamous cell carcinoma were on buccal mucosa. OSCC was most common of all oral malignancies of which most were in the older age group. Serious thought should be given to prevention and early detection

Analysis of total and available elements in medicinal plant moringa oleifera using atomic absorption spectrophotometer

Plant based medicaments have been man's prime therapeutic weapons to rescue him from the clutches of diseases. The role of elements particularly trace elements in health and disease is now well established. In this work, investigations have been made about a very important plant Moringa oleifera, which has traditionally played an important role particularly in the rural areas. It is a cheap source of protein, mineral rich food and an effective medicine against diseases. The aqueous extract of its leaves reduces blood pressure within a few minutes. In the present paper the analysis of Moringa oleifera for mineral elements was performed by using atomic spectrophotometer. The decoction of each part of the plant was also analyzed for different essential and trace elements. The samples of this plant were collected from surroundings of Hyderabad and voucher specimens were prepared following the standard herbarium techniques. Each part of this medicinal plant contains considerable amount of K, Mg, Zn, and Ca. These elements help to reduce the effect of hypertension