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1.
Indian J Pediatr ; 2008 Jul; 75(7): 751-3
Artículo en Inglés | IMSEAR | ID: sea-81095

RESUMEN

Low serum vitamin B(12) (V B(12)) and hyperhomocysteinemia have been reported in asymptomatic Asian Indian men. We studied the prevalence of V B(12) deficiency and hyperhomocysteinemia in 51 asymptomatic toddlers, from Pune, India. V B(12) levels were low and total serum homocysteine was high in 14% and homocysteine levels were significantly higher in boys. Programming for cardiovascular risk in adulthood possibly starts at a very young age through the homocysteine axis.


Asunto(s)
Estatura , Peso Corporal , Preescolar , Comorbilidad , Estudios Transversales , Dieta Vegetariana/estadística & datos numéricos , Femenino , Ácido Fólico/sangre , Homocisteína/sangre , Humanos , Hiperhomocisteinemia/sangre , India/epidemiología , Masculino , Prevalencia , Encuestas y Cuestionarios , Vitamina B 12/sangre , Deficiencia de Vitamina B 12/sangre
2.
Indian J Pediatr ; 2008 Apr; 75(4): 355-7
Artículo en Inglés | IMSEAR | ID: sea-83062

RESUMEN

OBJECTIVE: Of this pilot study was to assess the iron status and dietary intake of 1-3 year-old apparently healthy toddlers of the lower socio-economic class, and the effect of eight weeks intervention with liquid oral iron in an urban slum in Pune, India. METHODS: 50 toddlers (M= 25, F= 25) with mean age of 2.4 years (SD 0.82) were evaluated. Anthropometry, Food Frequency Questionnaire, a hemogram and ferritin were measured. Twenty mg of elemental iron was given to all toddlers. After 8 weeks clinical examination, anthropometry, hemoglobin (HGB) and Ferritin were measured. RESULTS: Prevalence of anemia was 66% (HGB <11 gm %) and ferritin (iron stores) were low (< 12 microgm/L) in 45 (90%). After therapy prevalence of anemia was 30%. There was a significant difference in the HGB and ferritin levels of children after eight weeks of therapy (p<0.001). CONCLUSION: The prevalence of anemia decreased from 66 to 30% after treatment with liquid iron. We propose that all concerned in the care of toddlers should join the fight against anemia and prescribe iron to all toddlers when they are seen for minor ailments.


Asunto(s)
Administración Oral , Anemia Ferropénica/diagnóstico , Preescolar , Relación Dosis-Respuesta a Droga , Esquema de Medicación , Femenino , Ferritinas/sangre , Compuestos Ferrosos/uso terapéutico , Estudios de Seguimiento , Hemoglobinas/análisis , Humanos , Incidencia , India/epidemiología , Lactante , Masculino , Proyectos Piloto , Áreas de Pobreza , Estudios Prospectivos , Medición de Riesgo , Índice de Severidad de la Enfermedad , Factores Socioeconómicos , Resultado del Tratamiento , Población Urbana
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