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1.
China Journal of Chinese Materia Medica ; (24): 3233-3237, 2020.
Artículo en Chino | WPRIM | ID: wpr-828453

RESUMEN

This paper introduces the application and financing of programs of efficacy material base of traditional Chinese medicine funded by the National Natural Science Foundation of China(NSFC), the Youth Science Fund and the Regional Science Fund from 2016 to 2019, and conducts analysis and summary in terms of research objects and analysis methods, with the aim to provide reference for applicants for programs of efficacy material base of traditional Chinese medicine.


Asunto(s)
China , Administración Financiera , Fundaciones , Medicina Tradicional China , Disciplinas de las Ciencias Naturales
2.
Acta Pharmaceutica Sinica ; (12): 813-820, 2010.
Artículo en Chino | WPRIM | ID: wpr-354570

RESUMEN

Heat shock protein 90 is a new target of antitumor drug, the inhibitor of Hsp90 fight against tumor by destroy and degrade the structure of protein. In recent years, looking for Hsp90 inhibitor is not only via structure modifying of natural products, but also via high throughput screening and computer aided drug design to find and synthesize new kinds of Hsp90 inhibitor. Anyway, Hsp90 inhibitor has considered as an important biology target and to pay more and more attention. This review describes recent developments of small molecule Hsp90 inhibitors.


Asunto(s)
Animales , Humanos , Adenina , Química , Farmacología , Anisoles , Química , Farmacología , Antineoplásicos , Química , Farmacología , Usos Terapéuticos , Benzoquinonas , Química , Usos Terapéuticos , Catequina , Química , Farmacología , Línea Celular Tumoral , Cristalización , Proteínas HSP90 de Choque Térmico , Química , Compuestos Heterocíclicos con 2 Anillos , Química , Farmacología , Lactamas Macrocíclicas , Química , Usos Terapéuticos , Macrólidos , Química , Farmacología , Estructura Molecular , Neoplasias , Quimioterapia , Patología , Pirazoles , Química , Farmacología , Relación Estructura-Actividad
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