1.
Indian J Physiol Pharmacol
;
1979 Oct-Dec; 23(4): 386-8
Artículo
en Inglés
| IMSEAR
| ID: sea-106750
Asunto(s)
Animales , Aminas Biogénicas/fisiología , Encéfalo/fisiología , Hipotálamo/metabolismo , Masculino , Melatonina/farmacología , Mesencéfalo/metabolismo , Neuronas/fisiología , Norepinefrina/metabolismo , Glándula Pineal/fisiología , Sistema Hipófiso-Suprarrenal/fisiología , Ratas , Serotonina/metabolismo
2.
Indian J Physiol Pharmacol
;
1976 Oct-Dec; 20(4): 216-20
Artículo
en Inglés
| IMSEAR
| ID: sea-108987
RESUMEN
The hypotensive drug alphamethyldopa, an inhibitor of serotonin synthesis, caused significant hypothermia ranging from 33.4 to 34.8 degrees C (t=3.09 at P less than 0.05) in four out of nine hypertensive patients, with evidence of cerebral atherosclerosis. The anti-serotonin effect of alphamethyldopa correlated with statistically significant (t=6.8 at P less than 0.001) fall in the 24 hour urinary 5-hydroxyindoleacetic acid on the third day of the therapy. The possible mode of hypothermic side effect is discussed.