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Asian Pac J Allergy Immunol ; 1988 Jun; 6(1): 23-8
Artículo en Inglés | IMSEAR | ID: sea-36977

RESUMEN

Lymphocyte subsets were studied in forty-nine patients with SLE using monoclonal antibodies and flow cytometry. A decrease in T4+ reactive cells (helper/inducer) was the most frequent observation. Decreased T4/T8 ratios were seen in patients with increasing clinically active disease, patients with positive anti-DS-DNA, positive anti-RNP antibodies and patients with low CH50 activity. However, low T4/T8 ratios were seen in patients with negative anti-Sm. Low T4/T8 ratios were also observed in patients taking prednisone at more than 10 mg/day and in patients treated with immunosuppressive drugs.


Asunto(s)
Adolescente , Adulto , Linfocitos T CD4-Positivos/inmunología , Femenino , Humanos , Inmunosupresores/uso terapéutico , Lupus Eritematoso Sistémico/tratamiento farmacológico , Masculino , Persona de Mediana Edad , Prednisona/uso terapéutico , Linfocitos T/clasificación
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