RESUMEN
Inflammatory bowel disease encompasses Crohn’s disease and ulcerative colitis and is characterized by uncontrolled, relapsing, and remitting course of inflammation in the gastrointestinal tract. Artificial intelligence represents a new era within the field of gastroenterology, and the amount of research surrounding artificial intelligence in patients with inflammatory bowel disease is on the rise. As clinical trial outcomes and treatment targets evolve in inflammatory bowel disease, artificial intelligence may prove as a valuable tool for providing accurate, consistent, and reproducible evaluations of endoscopic appearance and histologic activity, thereby optimizing the diagnosis process and identifying disease severity. Furthermore, as the applications of artificial intelligence for inflammatory bowel disease continue to expand, they may present an ideal opportunity for improving disease management by predicting treatment response to biologic therapies and for refining the standard of care by setting the basis for future treatment personalization and cost reduction. The purpose of this review is to provide an overview of the unmet needs in the management of inflammatory bowel disease in clinical practice and how artificial intelligence tools can address these gaps to transform patient care.
Asunto(s)
Humanos , Farmacogenética/normas , Psiquiatría/normas , Técnicas de Apoyo para la Decisión , Pruebas de Farmacogenómica/normas , Psiquiatría/métodos , Psicotrópicos/farmacología , Guías de Práctica Clínica como Asunto , Pruebas de Farmacogenómica/métodos , Trastornos Mentales/genética , Trastornos Mentales/tratamiento farmacológicoRESUMEN
Video assisted thoracoscopic surgery (VATS) is now an established technique for diagnostic and therapeutic intervention in patients with thoracic pathology at the Queen Elizabeth Hospital (QEH). This article reviews the experience with 50 patients over the period May 1996 to February 2003, looking at various factors and outcomes in an attempt to ascertain the viability of this procedure at this institution. It serves as a follow-up article to the publication of the initial experience in 1999 (1). There were 24 males and 26 females included in the study. Video assisted thoracoscopic surgery was used for diagnosis in 27 cases (54), therapeutic indication in 17 cases (34) and as both a diagnostic and therapeutic modality in six cases (12). In 92of cases, the operations were completed thoracoscopically with a conversion rate of 8. The morbidity and mortality rates were 18and 2respectively. Video assisted thoracoscopic surgery is an effective tool for the treatment and investigation of selected thoracic pathology at the QEH with complications and mortality rates comparable to other institutions (2, 3).
La cirugía toracoscópica asistida por video (CTAV) es ya una técnica establecida para el diagnóstico y la intervención terapéutica de pacientes con patologías toráxicas en el Hospital Queen Elizabeth. Este articulo pasa revista a nuestra experiencia con 50 pacientes en el transcurso del período de mayo de 1996 a febrero de 2003, prestando atención a varios factores y resultados en un intento por corroborar la viabilidad de ese procedimiento en nuestra institución. El trabajo sirve como un artículo de seguimiento a la publicación de nuestra experiencia en el año 1999(1). El estudio abarcó 24 hombres y 26 mujeres. La CTAV se usó para el diagnóstico en 27 casos (54%), como indicación terapéutica en 17 casos (34%), tanto en la modalidad de diagnóstico como en la terapéutica en seis casos (12%). En el 92% de los casos, las operaciones fueron completadas toracoscópicamente con una tasa de conversión de 8%. Las tasas de morbilidad y mortalidad fueron 18% y 2% respectivamente. La CTAV resultó ser un instrumento efectivo para el tratamiento y la investigación de patologías toráxicas seleccionadas en nuestra institución, con complicaciones y tasas de mortalidad comparables a la de otras (2) (3).