Colorectal carcinoma; frequency in adult patients presenting with large bowel obstruction

Introduction: Large bowel obstruction due to colorectal carcinoma occurs in up to 20% of the patients and usually accompanied by morbidity and mortality[2-4]. Almost 25 % deaths occur post-operatively following surgery for colorectal cancers occur in those who initially present with obstruction[1]. Usually elderly patients with associated co-morbidities presents with bowel obstruction

Objective: Find out the frequency of colorectal cancers in patients presenting with large bowel obstruction

Design: Prospective cross sectional study

Setting: Shaikh Zayed Hospital Lahore

Period: from 31st December 2010 to 31st December 2012

Materials and Methods: A total 20 patients were presented with large bowel obstruction with the age ranges between 40 to 70 years. All the 20 patients underwent routine haematological and biochemical tests. In these patients an abdominal x-ray in a supine or standing position was taken and dilated loops of bowel, air-fluid interfaces, or both was observed then Contrast radiography [Barium/gastrograffin] was done to define the site and extent of the obstruction. An abdominal computed tomography scan was done to evaluate the extent of the disease. Colonoscopy was also carried out in the patients with colorectal cancers to find out the size and location of the tumor and biopsy taken by colonoscope

Results: 12 patients out of 20 presented with large bowel obstruction were diagnosed to have a colorectal cancers and the age ranges from 60 to 70 years. The 8 patients were diagnosed to have a sigmoid colonic tumour and 4 patients were suffering from a tumour of recto sigmoid junction. Whereas in rest of the 8 patients the large bowel obstruction was due to other benign causes like volvulus and intussusception and age range was 50 - 60 years. 6 patients were suffering from sigmoid volvulus and remaining 2 had colo-colic intussusception

Conclusions: It is concluded that the major cause of the large bowel obstruction is the left sided colorectal cancers the tumours of recto sigmoid junction

Multiple angiosarcomas of the gut (duodenum, appendix and cecum) - a case report

Angiosarcoma is a rare soft-tissue neoplasm that occurs most often in the skin and the subcutaneous tissues but very rarely in the gastrointestinal tract. We present a case of angiosarcoma involving small and large intestine

Carcinoma of breast experience at sheikh Zayed hospital lahore

Breast carcinoma is a common malignancy in females. [1] To review the modes of treatment [2] To see the corelation of size of tumour with nodal spread DESIGN. Reterospective study SETTING: Sheikh Zayad Hospital Lahore PERIOD: Three years [Jun 1991 -Jun 1994] MATERIAL AND METHODS. 105 patients were studied 101 patients were females and 4 patients were males. Various modes of surgery were noted. Post operative adjuvant therapy, hormone manipulation, radiotherapy and chemotherapy were noted. Mean age was 45,6 years. infiltrating ductal carcinoma was seen in 86.64% patients left breast involvement was 54.28% right breast involvement was seen in 42.85% cases. Mean lymph node invoivemny was 11 and5.24% cases were diagnosed in early ivasive stage [T[2] N[1]M0] CONCLUSIONS: Modified radical mastectomy provides good loco regional control of the disease, adjuvant therapies help to take care of possible spread of tumour