RESUMEN
Background: Preterm labour occurs due to various causative factors. Genital infections contribute significantly to the preterm labour. Ours is a prospective, observational study looking at the cervical microbiota involved in the preterm labour. The cervical flora contributing to the occurrence of preterm labour was studied. The results were analyzed based on the microbiological study of cervical swabs. The primary objectives of this study were to determine the association of cervical microbiota of pregnant women with spontaneous preterm delivery. To characterize the effect of cervical microbiota on birth gestation. The secondary objective of this study was to analyse the role of cervical microbiota and its relationship between social and behavioural factors.Methods: It is a prospective, observational study, which includes 193 patients, studied over a period of one and a half year. It was conducted at our tertiary care centre after the approval by ethics committee, and the results were analysed. As this is a purely observational study, management decisions of treating obstetrician were not interfered with. No additional cost, intervention or injury was caused to the study subject.Results: In our study, cervical swab culture shows growth in 2.07% which is statistically insignificant. Though, it was found that preterm labour is more common with leucocytosis, i.e. WBC > 11000 cmm, which is found to be statistically significant (p value = 0.023).Conclusions: In our study, we found that there was no significant association of cervical flora with preterm labour, though we found an association with leucocytosis.
RESUMEN
Background: Diagnosis of diabetes in pregnancy is an important public health issue. Present study was done to study incidence of abnormal foetal 2D echocardiography in women with diabetes and gestational diabetes mellitus and to know their obstetric outcome.Methods: It is a prospective, observational study, which includes 80 patients. It was conducted at our tertiary care centre after the approval by ethics committee, and the results were analysed.Results: Out of 80 patients included, 77% women had GDM and rest 23% had DM. In this study, all patients had fetal 2D echocardiography done. 3 patients had report suggestive of congenital heart disease in the fetus. 1 of them was suggestive of TAPVC, 1 was suggestive of enlarged right atrium, 1 report was suggestive of VSD. Two of the abnormal fetal 2D echocardiography diagnosis of TAPVC and VSD was confirmed by neonatal 2D echo. One baby with Normal antenatal 2D echo had ASD on post-natal evaluation. The baby with antenataly enlarged right atrium had no cardiac anomaly on post-natal evaluation.Conclusions: Incidence of DM/GDM is increasing. As baby is likely to have congenital anomalies, out of which cardiac anomalies are most common, fetal echocardiography is a well-established, accurate, and safe method for diagnosing congenital heart disease. All the babies with abnormal fetal echocardiography need post-natal confirmation.