Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Añadir filtros








Intervalo de año
1.
Chinese Journal of Natural Medicines (English Ed.) ; (6): 471-480, 2015.
Artículo en Inglés | WPRIM | ID: wpr-812519

RESUMEN

A method coupling ultra-performance liquid chromatography (UPLC) with quadrupole time-of-flight mass spectrometer (Qtof MS) using the electrospray ionization (ESI) source was developed for the identification of the major saponins from Panax notoginseng powder (PNP). Ten different PNP samples were analyzed and evaluated for their quality by similarity evaluation and principle component analysis (PCA). Based on the accurate mass, summarized characteristic fragmentation behaviors, retention times of different types of saponins, related botanical biogenesis, and reported chromatographic behavior of saponins, fifty-one common peaks were effectively separated and identified, including 28 protopanaxadiol saponins and 18 protopanaxatriol saponins. Simultaneously, 15 significant discrepancy compounds were identified from the disqualified PNP samples. The established UPLC/Qtof MS fingerprint method was successfully applied for profiling and identifying the major saponins of PNP, providing a fast quality evaluation tool for distinguishing the authentic PNP and the adulterated products.


Asunto(s)
Cromatografía Líquida de Alta Presión , Métodos , Medicamentos Herbarios Chinos , Química , Panax notoginseng , Química , Polvos , Química , Espectrometría de Masa por Ionización de Electrospray , Métodos
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA