Twin-twin transfusion syndrome; TTTS / 대한산부인과학회지

Twin-twin transfusion syndrome (TTTS) is a complex cardiovascular disease affecting monochorionic (MC) twin pregnancies, and has a high perinatal mortality rate. Its pathogenesis remains poorly understood, but TTTS involves unbalanced transfusion of blood from a donor to a recipient along one or more placental arteriovenous anastomosis in absence of adequate compensatory superficial counter-transfusion. Recent data demonstrated laser ablation to be better than amnioreduction, especially when the condition develops before 26 weeks of gestation.