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Indian J Exp Biol ; 1992 Aug; 30(8): 756-8
Artículo en Inglés | IMSEAR | ID: sea-57214

RESUMEN

Photoreactivation of UV-irradiated DSNA with phr A photolyase from Escherichia coli was studied in the presence of yeast RNA. Mixing of RNA with UV-irradiated DNA before its treatment with photolyase inhibited the photoreactivation of DNA. Denatured (by sonication) RNA was found to be more effective in blocking photolyase action. Agarose gel electrophoresis experiments suggest that this inhibition of photoreactivation is due to interference in the binding of photolyase with UV-irradiated DNA by yeast RNA.


Asunto(s)
ADN/efectos de la radiación , Daño del ADN/efectos de los fármacos , Reparación del ADN/efectos de los fármacos , Desoxirribodipirimidina Fotoliasa/fisiología , Escherichia coli/enzimología , Haemophilus influenzae , ARN de Hongos/farmacología , Rayos Ultravioleta/efectos adversos
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