Malignancy Rates of Suspicious Breast Lesions in Patients on Annual Screening or Regular Follow-up Ultrasonography

PURPOSE: The objective of this study is to investigate the malignancy rates of BIRADS 4 and 5 lesions detected on annual screening or follow-up US and to correlate the malignancy rates with the rationales for biopsy. MATERIALS AND METHODS: Between 2010 and 2011, among 2837 patients who underwent US-guided core-needle biopsy, 423 patients underwent screening or regular follow-up US examinations. Lesions were classified into four groups: newly detected suspicious lesions, benign lesions with interval growth, benign lesions with suspicious changes of US features and benign lesions with interval growth and suspicious changes of US features. RESULTS: The malignancy rates were as follows: BI-RADS 4A low suspicion of malignancy, 8.1% (31/379); 4B intermediate suspicion of malignancy, 56% (14/25); 4C moderate suspicion of malignancy, 71.4% (10/14); 5 highly suggestive of malignancy, 100% (5/5). The malignancy rates for the four groups were as follows: newly detected suspicious lesions, 17.46% (51/292); benign lesions with interval growth, 7.77% (7/90); benign lesions with suspicious changes of US features, 4% (1/25); benign lesions with interval growth and suspicious changes of US features, 6.25% (1/16). Comparison of the malignancy rate of newly detected suspicious lesions with that of benign lesions with interval growth revealed a statistically significant difference (p=0.038). No significant differences were observed between the other groups (p>0.05). CONCLUSION: The malignancy rates of suspicious lesions detected on annual screening or follow-up US were similar to those of the reported BI-RADS data. A higher malignancy rate was observed for newly detected suspicious lesions than for lesions with interval growth.

Analysis of Foods and Nutrients Intake Obtained at the Final Probing Step in 24-hour Recall Method

This study was conducted to examine the usefulness of adding final probing step (step3) in dietary assessment by 24-hour recall method among Korean adults. One-hundred fifty five adults (37 males and 118 females) above 30 years of age who visited hospitals for health examination were recruited at three hospitals in Korea. One day dietary intake was obtained using 24-hour recall method from each subject. Dietary interview was conducted in 3 steps, (1) quick list of foods eaten during the previous day, (2) detailed information of all the foods eaten, (3) the final probing for any items forgotten. Items added at the step3 were identified and contributions of energy and nutrient intakes were calculated. The average duration of interview was 10.5 min, and time spent for each step was 4.12 minute for step 1, 5.62 minute for step 2, and 38 second for step 3. The average number of dishes reported by the subjects added at the step 3 was 2.2. (Males = 2.6, Females = 1.6) Frequently reported dishes in the step 3 were Beverage, Tea, alcohol (37.1%) and Fruits (31.8%). From mean total energy intake of 1,589 kcal (Men = 1,846 kcal, Women = 1,509 kcal), 179 kcal (11.3%) was added at the step 3. In the step 3, nutrient intakes increased significantly except retinol in total subjects and except retinol and cholesterol in males but all nutrients increased significantly in females. The final probing step can add significant information on intakes of foods and many nutrients with only about 38 seconds of interview time. Confirmation of the results with larger samples of different age groups is needed.