Haematological side effect of Helicobacter pylori eradication

The effect of Helicobacter pylori infection on systemic disorders is not well understood. This study was to evaluate the effect of H. pylori eradication on blood count, differential leucocytic count and RBCs indices. In this study, atotal of 115 H. pylori positive patients underwent eradication triple therapy for one week, with cured 100 patients. Complete blood count, RBCs indices and differential leucocytic count were analyzed before 2 and 12 weeks after eradication for the cured patients. The results showed that two weeks after H. pylori eradication, platelets count significantly increased but total leucocytic counts and neutrophils were significantly reduced. After three months, RBCs count, Hb concentration, MCV and MCHC were significantly increased, but lymphocytic counts was significantly reduced

Correlation of serum lipid in infective disease and infective hepatitis

Dylipidaemia is a disorder of lipid metabolism. It is either primary due to familial, genetic factors or secondary due to environmental metabolic, infection or drugs. In this study, we evaluated the prevalence of dyslipidemia in 78 patients with infectious disease and infective hepatitis. 78 patients with acute infection and 20 controls were classified into group I: 24 patients with gram positive Cocci, group II: 24 patients with gram negative Bacilli, group III: 30 patients with acute infectious hepatitis and group IV: 20 normal as control. There were hyperlipidaemia with significant increase in cholesterol and triglycerides [P<0.001], alpha [P<0.05] and beta lipoproteins [P<0.01] and significant decrease in prebeta lipoprotein [P<0.001] in acute infectious hepatitis. A significant low level of prebeta lipoprotein is due to decrease synthesis by the liver during infection, hyperlipidemia is an index to the progress of the infection and APO E has physiological role in protection against lipo polysaccharide endo-toxemia and sepsis and can be used therapeutically