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Objective：To research studies on patients with head and neck cancer who underwent laryngectomy (patients with laryngectomy) in terms of function, activity, participation, and environment, and examine quality of life (QOL) -related factors.Methods：The participants were patients who underwent laryngectomy and belonged to the Japanese Laryngectomy Clubs. We investigated basic attributes, QOL, sarcopenia, neck and upper limb function, and upper limb-related activities of daily living (ULADL). Statistical analysis was performed using multiple logistic regression analysis after correlation analysis to investigate QOL-related factors.Results：The number of valid responders was 272 patients, median age was 74.0 years, median postoperative follow-up was 8.7 years, and 94 were still employed after surgery. Multiple logistic regression analysis results revealed that factors related to QOL included ULADL, sarcopenia, and neck and upper limb function.Conclusions：The QOL-related factors of laryngectomy were neck and upper limb function, ULADL, and sarcopenia. Rehabilitation for these factors is considered important in improving QOL.
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In Japan, based on the Ministry of Health, Labour and Welfare’s “Pharmacy Vision for Patients” (2015), there has been a growing need to shift from “drug-centered, physical work” to “patient-centered, interpersonal work.” Medication counseling is one of the most important tasks of pharmacists. In the present study, we focused on the questions asked by patients during medication counseling, and statistically analyzed the content of the questions and the patient attributes obtained from the patient medication profile. The study was conducted from 2018 to 2019 on patients who visited two pharmacies. Data from a total of 3,300 patients was collected, of which 859 asked questions during medication counseling, accounting for about 26% of the total. Attributes that significantly influenced the asking of questions included gender, new prescriptions, and who was being instructed, especially for women and parents of infants. In terms of topic, questions about the duration and timing of taking the medication and about the medication itself were common in all departments. In terms of medication effects, there were many questions about topical and central nervous system medications, but there were also questions about non-medication matters such as tests. When providing medication counseling, it is expected that pharmacists will actively provide instructions to resolve patients’ questions based on the characteristics of each pharmacy and on patient demographics, as well as improve the quality of interpersonal services according to the patient’s background.
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<p><b>OBJECTIVE</b>To evaluate the accuracy of Cercon CAD/CAM system and the influence of different spacer thickness and spacer coverage area on the internal and marginal fit of the copings.</p><p><b>METHODS</b>A stainless steel master model of first molar was replicated. After scanning, designs of copings were made with different spacer thickness and spacer coverage area. There were six groups: S10C70, S10C90, S30C70, S30C90, S60C70, S60C90. Measurements of the adaptation were performed with silicone impression material and an image analysis system.</p><p><b>RESULTS</b>Univariate ANOVA showed that variation in the internal fit of copings was related to measuring location, spacer thickness and spacer coverage area. There was significant difference between different spacer coverage area groups, and significant difference between spacer thickness 10 microm and 30 microm groups, 10 microm and 60 microm groups, no significant difference between spacer thickness 30 microm and 60 microm groups. Mean marginal fit was (27.7+/-7.6) microm. There was statistically significant difference between both mesial, distal marginal gaps and both buccal, lingual marginal gaps. No difference between mesial and distal marginal gaps, and between buccal and lingual marginal gaps.</p><p><b>CONCLUSION</b>The accuracy by Cercon CAD/CAM system for the marginal and internal fit of zirconium dioxide copings is well within the range of clinical acceptability. Spacer thickness and spacer coverage area have statistically significant influence on the internal fit.</p>