Have You Ever Heard about Meralgia Paresthetica?

Meralgia paresthetica (MP), first described in 1878, is a sensory mononeuropathy of the lateral femoral cutaneous nerve (LFCN) characterized by pain, tingling, numbness, and paresthesias localized to the anterolateral thigh. There are many etiologies for MP, including those that are spontaneous (idiopathic, metabolic or mechanical) and iatrogenic (surgery, trauma). A 46-year-old female came to our emergency department (ED) with a right hip pain that developed after two days of an altered mental status from high amounts of multiple drugs (benzodiazepine, SSRI, and antipsychotics) to commit suicide. Her past medical and surgical histories were unremarkable. In addition, her vital signs were stable and her electrocardiography was unremarkable. On the other hand, laboratory tests showed an elevated creatinine kinase 14787 IU/L (normal range, 26~140 IU/L) and urine myoglobin >1000 ng/mL (normal range, 0~10 ng/mL). She was admitted to our ED for the management of rhabdomyolysis. The patient didn't slip down and slept on her right side for a long period. An initial pelvis and femur x-ray ruled out a fracture and a straight leg raise test was negative. We took a lumbar spine x-ray to rule out a herniated intervertebral disk because she complained of pain in the second and third lumbar distribution of her right thigh. These x-rays were unremarkable. We presumed she had a hip and thigh contusion and gave her painkillers, but her symptoms did not improved. After a day, the patient complained of numbness (5/10) rather than pain. We then suspected peripheral neuropathy. Her electromyography and nerve conduction velocity confirmed right LFCN neuropathy, MP. MP is often clinically diagnosed and treated conservatively. It is a neurologic disorder due to the entrapment of the LFCN. This case shows that a long period lacking in movement can cause MP. In future cases, the possibility of peripheral neuropathy should be considered, especially in mentally altered patients after drug intoxication.

A Case of Delayed Administration of Naloxone for Morphine Intoxicated Patient

Opioids are the one of the most commonly used drugs to control cancer pain all over the world. But, we should not overlook the potential risk of opioid intoxication because they have well-known detrimental side effects. The opioid intoxication can be diagnosed thorough various clinical manifestations. The altered mental status, respiratory depression, and miosis is very representative clinical features although these symptoms don't always appear together. Unfortunately the opioid-toxidrome can be varied. A 42 years old man came to our emergency room after taking about 900 mg morphine sulfate per oral. He was nearly alert and his respiration was normal. Even though his symptoms didn't deteriorated clinically, serial arterial blood gas analysis showed increase in PaCO2. So we decided to use intravenous naloxone. Soon, he was fully awaked and his pupils size was increased. After a continuous infusion of intravenous naloxone for 2 hours, PaCO2 decreased to normal range and his pupil size also returned to normal after 12 hours. Though the levels of serum amylase and lipase increased slightly, his pancreas was normal according to the abdominal computed tomography. He had nausea, vomit, and whole body itching after naloxone continuous infusion, but conservatively treated. We stopped the continuos infusion after 1 day because his laboratory results and physical examinations showed normal. As this case shows, it is very important to prescribe naloxone initially. If you suspect opioid intoxication, we recommend the initial use of naloxone even though a patient has atypical clinical features. In addition, we suggest intranasal administration of naloxone as safe and effective alternative and it's necessary to consider nalmefene that has a longer duration for opioid intoxication.

The Clinical Utility of Blood Cultures by Pneumonia Severity Index for Patients with Community-Acquired Pneumonia in the Emergency Department

PURPOSE: Community-Acquired Pneumonia (CAP) is a common cause of mortality and serious morbidity. Regardless of the condition of the patients, almost all are hospitalized. And it seems to be a standard procedure to obtain blood cultures before the administration of antibiotics in suspected pneumonic patients. Recent studies show that the blood cultures don't affect the treatment of the patients with CAP. Accordingly, this study was designed to examine the usefulness of the blood cultures routinely performed and to evaluate the stratification of the patients with CAP by Pneumonia Severity Index (PSI) in the Emergency Department (ED). METHODS: Research subjects were patients over 16 years old who had been diagnosed with CAP in a general hospital between January and December 2008 and were admitted by way of the ED. We evaluated their records retrospectively. RESULTS: A total of 261 patients were diagnosed with CAP. According to the PSI, 155 (59%) of the 261 were classified as being in the low risk group and 106 (41%) in the high risk group. Blood cultures were positive in 13 of 261 (5%). Three of 13 patients belonged to the low risk group, and 10 to the high risk group. Antibiotics were changed in 43 of 261 patients. Nineteen of those belonged to the low risk group and 24 to the high risk group. Of the 13 bacteremic patients, blood cultures results altered therapy for 4 patients. CONCLUSION: Most often, blood cultures performed in the ED do not alter the therapy of patients with CAP. But we do recommend blood cultures for the high risk group.

Rhabdomyolysis after Lamotrigine Poisoning: A Case report

Lamotrigine is a newer anti-epileptic drug for adjunctive treatment of refractory epilepsy, partial seizures, generalized tonic-clonic seizures, and bipolar disorder. Lamotrigine overdose causes serious central nervous and cardiovascular problems, but reports are uncommon. Few lamotrigine overdoses have been described because anti-epileptic drug use is limited and usually used with combination of other anti-epileptic drugs. In addition, most patients visit emergency departments with multi-drug overdoses, so few cases of lamotrigine poisoning alone exist. We had a female patient visit our emergency department a couple of hours after a lamotrigine overdose treated with intravenous hydration and urine alkalization by NaHCO3. She recovered successfully without any evidence of renal injury. However, she developed profound rhabdomyolysis, a previously unreported complication of this medication. We suggest that serial creatine kinase levels should be measured after lamotrigine poisoning.

Do You Follow The ACLS Guideline?

PURPOSE: In 2000, the American Heart Association and International Liaison Committee on Resuscitation published guidelines for CPR (Cardiopulmonary Resuscitation), and these guidelines were revised in 2005. Many physicians perform CPR differently than suggested by these guidelines. We investigated guideline conformation rates for CPR by non-emergency physicians. METHODS: From January 1st, 2005, to December 31st, 2005, and from January 1st, 2007, to September 30th, 2007, 103 in-hospital CPR cases were enrolled. We separated the 103 cases into two groups: 2005 patients and 2007 patients. Fifty-two cases in the 2005 group and 51 cases in the 2007 group were enrolled. The defibrillation method, defibrillation energy, epinephrine use, and atropine use were analyzed. RESULTS: Nineteen cases (82.6%) in the 2005 group and three cases (21.4%) in the 2007 group were performed using the appropriate defibrillation method (p=0.0002). Seventeen cases (73.9%) in the 2005 group and four cases (28.6%) in the 2007 group received the appropriate defibrillation energy (p=0.0069). Seven cases (14.0%) in the 2005 group and 16 cases (32.0%) in the 2007 group used the appropriate epinephrine dose (p=0.0325). Fourteen cases (28.0%) in the 2005 patient group and 14 cases (29.2%) in the 2007 patient group used the appropriate atropine dose (p=0.8983). CONCLUSION: Although CPR guidelines were renewed in 2005, many physicians do not follow these guidelines. We suggest that adequate information, education, feedback, and further study are needed for guideline conformation.

The Effect of an Alerting Call with a Cellular Phone on Emergency Care for Critically Ill Patients

PURPOSE: The overcrowding of the ECC (Emergency Care Center) is a significant problem for most general hospitals. This overcrowding can be a potential cause of undesirable outcomes in critically ill patients. The purpose of this study was to evaluate the effect of an alerting call, with a cellular phone, before the presentation of critically ill patients in overcrowded emergency care centers. METHODS: One hundred and two patients with cardiac arrest, altered mental status, dyspnea, and chest pain were brought to the emergency care center by 119 EMS (Emergency Medical Transport System) from July 2007 to August 2007 and March 2008 to April 2008 and were enrolled in this study. The EMS made 39 alerting calls with a cellular phone before arrival to the ECC. Each alerting call was answered by the senior resident emergency physician over a 24 hour period. We prospectively reviewed the data and compared the cases with an alerting call to those without such a call. RESULTS: Thirty-nine (38%) patients arrived at the ECC with an alerting call and 63 (62%) without one. The general characteristics between the two groups were not different. The mean duration for the initiation of care for the patients with a cardiac arrest, with an alerting call, was faster than for those who arrived without an alerting call; the difference in the start of compressions was significant (p=0.006). For patients with altered mental status, all variables studied showed a significant statistical difference (p<0.001) between the two study groups. For acute dyspnea and chest pain, the first set of vital signs (p=0.004) and the ABG (p=0.001) were significantly different between the two groups. The mean time to the initiation of care was faster for the patients with an alerting call than for those without an alerting call. CONCLUSION: The initiation of care in critically ill patients was significantly faster with a cellular phone alerting call before the patient's arrival to the ECC. Therefore, an alerting call from the 119 EMS to the ECC appears to improve the time to initiating emergency care of critically ill patients in the ECC.

Reliability and Validity of the Modified Emergency Severity Index-2 as a Triage Tool

PURPOSE: We measured the inter-rater reliability and validity of the modified Emergency Severity Index-2 ((m)ESI-2) as a triage tool in the emergency department (ED). METHODS: We applied (m)ESI-2 to 2,724 patients who visited three EDs. In each ED, emergency medicine residents, interns, and nurses independently evaluated the severity of the patient with (m)ESI-2. Data on the triage result, the patient disposition, and the length of stay in the ED were collected prospectively. For patients who were admitted or who stayed more than 24 hours in the ED, the APACHE II score was calculated. RESULTS: The weighted kappa value was 0.602 between residents and interns, 0.541 between residents and nurses, and 0.451 between interns and nurses. Hospitalization (ED death, admission, transfer) rates were 100% in category 1 and 82.4%, 53.8%, 17.2%, 6.2% in categories 2 through 5, respectively. The mean length of stay was longest in category 3 (687 min) and shortest in category 5 (150 min). The mean APACHE II score was highest in category 1 (10.8) and 8.6, 6.2, 5.2, 2.9 in categories 2 through 5, respectively. CONCLUSION: The (m)ESI-2 demonstrated good to fair interrater reliability among residents, interns, and nurses, and the resultant categories were related with the hospitalization rates, the length of stay in the ED, and the APACHE II score. With further modification and refinement, (m)ESI-2 can be a reliable and a valid triage tool in the ED.