Association between Skin Phenotype and Apocrine Bromhidrosis in Koreans / 대한피부과학회지

BACKGROUND: The diagnosis of bromhidrosis is a clinical one, but the definition of "normal" odor is a poorly defined term. In the Asian population, the presence of even a faint odor is considered diagnostic. For the more exact evaluation, it is vital to study more findings associated with bromhidrosis. Recently, several studies have suggested possibility that the activity of sebaceous gland may be increased in patients with bromhidrosis. OBJECTIVE: The aim of this study was to compare the differences of the seborrheic phenotypes and the measured serum level of facial skin surface between patients with bromhidrosis and the normal population. METHODS: Twenty patients who were diagnosed with bromhidrosis by nose smell test and age-matched twenty from the normal population were evaluated with regard to the presence of seborrheic skin phenotypes suggested by Ely. We also measured sebum level of facial skin by Sebumeter(R). RESULTS: The presence of some seborrheic skin phenotypes such as telangiectasia and square palm were increased significantly in the patients. In addition, objectively measured sebum of facial skin surface was relatively increased in the patients. CONCLUSION: We concluded that there is an association between apocrine bromhidrosis and seborrheic skin phenotype.

A Case of Plasma Cell Cheilitis / 대한피부과학회지

Plasma cell cheilitis is an idiopathic, benign, inflammatory mucosal condition characterized histologically by a dense band-like infiltrate of plasma cells in the upper dermis of the mucosa. In addition to the lips, the disease can affect the penis, vulva, buccal mucosa, palate, gingiva, tongue, epiglottis, and larynx. Plasma cell cheilitis of the lip appears as a circumscribed, flat to slightly elevated, eroded area, usually on the lower lip of an elderly person. We report a 70-year-old man who had a well-demarcated, erythematous, erosive lesion on his lower lip for 1 year. A biopsy specimen showed an upper dermal infiltrate that consisted mainly of plasma cells. Oral griseofulvin, 500mg/day, was begun, and 8 weeks later the lesion showed marked improvement.

A Case of Nail Changes Secondary to Docetaxel / 대한피부과학회지

Docetaxel is a new taxoid antineoplastic drug widely used for advanced breast cancer , ovarian cancer . Skin and nail toxicity are one of the more frequent nonhematologic adverse reactions. Especially, nail changes include dark pigmentation, subungual hemorrahage, acute paronychia, onycholysis, Beau s line etc. We have observed a striking example of multiple Beau s lines from all fingernails and toenails in a man receiving a docetaxel infusion for treatment of metastatic cancer with unknown-origin.

A Case of Localized Follicular Hamartoma with Pili Multigemini / 대한피부과학회지

Follicular hamartoma is a rare, benign adnexal tumor with varieties of clinical diversity. But, Histological feature is characterized by a proliferation of immature hair follicle in the dermis with multifocal islands and thickened perifollicular sheath. Pili multigemini is also a rare, developmental anomaly of hair growth with multiple hairs from two or more matrices and papillae in a single pilosebaceous unit. Its prevalence and pathogenesis are unknown. We describe herein a rare case of localized follicular hamartoma with pili multigemini suggesting the possibility of association on pathogenesis between them.

A Case of Eccrine Porocarcinoma / 대한피부과학회지

Eccrine porocarcinoma is a very rare, locally aggressive, potentially fatal tumor arising from the intraepidermal ductal portion of the eccrine sweat gland. It develops either spontaneously or from a long standing benign eccrine poroma. It usually affects older persons and is located most commonly on the lower extremities. It is a slow growing tumor and clinically resembles other skin cancers. We report a case of eccrine porocarcinoma in a 57-year-od man. In this case, the tumor was located on the volar aspect of the right thumb, showing verrucous-surfaced, crusted nodular appearance. There was no evidence of metastasis.

A Case of Clear Cell Syringoma / 대한피부과학회지

Ansan, KoreaClear cell syringoma is a rare variant type of syringoma. It has two noteworthy features: histologic preponderance of clear cells and frequent coexistence with diabetes mellitus. There is no difference between clear cell syringoma and typical syringoma with respect to age, sex, and clinical features. We report a 48-year-old woman who presented with clear cell syringoma concomitant with diabetes mellitus. Histopathologic findings showed numerous various-sized, well-defined tumor cell nests composed largely of clear cells.

A Case of Multiple Basal Cell Carcinomas

The multifactorial etiology of BCC(basal cell carcinoma) are incompletely understood, including factors leading to multiple lesions in some patients. Cases of multiple BCCs reported in the literature have been associated with UV irradiation, inorganic arsenic poisoning, X-ray therapy, hematologic malignancy and several genodermatoses such as nevoid BCC syndrome, albinism, xeroderma pigmentosum. Multiple BCCs presented on the sun-protected areas, lacking predisposing risk factors which have been known, is rare skin condition. However, it suggests that there may be an unknown genetic susceptibility to the development of multiple BCCs. We report a rare case of multiple BCCs, which had developed only on the sun-protected areas in 64-year-old man, without any known predisposing causes.

A Case of Mondor's Disease / 대한피부과학회지

Mondor's disease is a uncommon disorder characterized by superficial thrombophlbitis, classically of thoracoabdominal wall. In about 50%-60% of cases, the cause is not determined, whereas in the others it is due to primary or secondary hypercoagulation requiring careful investigation. A 30-year- old woman presented a cord-like tender subcutaneous lesion on the left thoracoabdominal wall and histologic finding reveals thrombophlebitis. We found no evidence for primary and secondary hypercoagulable states.