RESUMEN
BACKGROUND: Pilomatricoma is a rare benign follicular tumor in Orientals. OBJECTIVE: Clinical and histopathological features of the tumor were analyzed. METHODS: The medical records and histopathological slides of 19 tumors from 17 patients with pilomatricoma were studied. RESULTS: The morphology of the tumors were divided into 3 groups :1) elevated, uniform nodules(16 cases), 2) elevated, multilobulated nodules(2 cases), and 3) non-elevated, uniform nodules (1 case). Histologically, the tumors were composed of shadow cells, transitional cells, basaloid cells and squamous cells. Changes of the stroma within the tumors and the stroma overlying the tumors included vascular dilatation, RBC engorgement and infiltration of inflammatory cells. Changes of the epidermis overlying the tumors were found in 14 cases and included hyperkeratosis(14 cases), follicular plugging(2 cases), epidermis invagination(5 cases) and acanthosis nigricans-like change(3 cases). CONCLUSION: Clinically, pilomatricomas manifested as either a solitary nodule or two nodules. Histologically, several tumors showed palisading of basaloid cells, retraction spaces, lymphoid follicles and acanthosis nigricans-liike epidermal changes in addition to the classic features of pilomatricoma.
Asunto(s)
Humanos , Dilatación , Epidermis , Registros Médicos , PilomatrixomaRESUMEN
We report a case of adenoid squarnous cell carcinoma occurred in a 64-year-old male. The patient had a single, centrally ulcerated nodule with an indurated border on the superior helical rim of the left ear. The histopathologic finding showed a squamous cell carcinoma infiltrating der mis as multiple gland-like structures. The wall of gland-like structure was composed of one to several cell layers and the lumen was filled with dyskeratotic, acantholytic cells.
Asunto(s)
Humanos , Masculino , Persona de Mediana Edad , Tonsila Faríngea , Carcinoma de Células Escamosas , Oído , ÚlceraRESUMEN
Mucoceles usually occur as solitary, asymptomatic, translucent, and dome-shaped cysts containing clear viscous fluid on lower lip or oral mucosa. The authors reviewed the clinical and histopathological findings in 33 patients with mucocele and attempted to clarify the difference between the histopathologic types (retention and extravasation). The results were summarized as follows. 1. Age distribution was from 2 to 53 years and mean age was 21.4 years. Male to female ratio was 1.2:1(18 males.15 females). 2. Histopathologic type was classified. 4 cases(12.1%, mean age.17.3 years) were retention type, 19 cases(57.6%, mean age.'21.5 years) mixed type, and 10 cases(30.3 %, mean age.20.9 years) extravasation type. Among 19 mixed types, 13 cases were retention dominant and 6 cases extravasation dominant. 3. Durations from the onset to the diagnosis could be clarified in 16 cases. Those were below 1 year in 14 cases(87.5% ) and below 3 years in 16 cases all. Mean duration was 9.4 months. 4. The sites of involvement were lower lip(72.7%), tongue(24.3%), and oral mucosa(3.0%), in decreasing order of frequency. 5. The visited departments were otolaryngology(72.7%), dentistry(12.1%), plastic surgery(9,1%) and dermatology(6.1%), in decreasing order of frequency. 6. In the histopathologic observation, surface epithelium was observed in 25 cases (75.8%), cyst in 23 cases(69.7%), granlation tissue in 29 cases(87.9%), mucin in 28 cases(84.8%), surrounding salivary glands in 20 cases(60.6%) and foamy macrophages in 32 cases(97.0% ), 7. Special stains(PAS, D-PAS, and alcian blue at pH2.5 and 0.4) for the mucin were performed in 10 cases. The results were compatible with sialomucin.