Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
Añadir filtros








Intervalo de año
1.
West China Journal of Stomatology ; (6): 211-213, 2005.
Artículo en Chino | WPRIM | ID: wpr-300334

RESUMEN

<p><b>OBJECTIVE</b>To observe the expression of urokinase-type plasminogen activator (uPA) in human tongue squamous carcinoma cells (Tca8113) under hypoxia, in order to explore the relation between hypoxia and invasion and metastasis of oral cancer.</p><p><b>METHODS</b>Under different hypoxic times(0, 3, 6, 12, 24 h), the expression of uPA protein was examined quantitatively using immunohistochemical technique (IH) and flow cytometry (FCM).</p><p><b>RESULTS</b>Hypoxia promoted the expression of uPA. The longer hypoxic time was, the higher expression of uPA was.</p><p><b>CONCLUSION</b>Hypoxia can promote invasion and metastasis of oral squamous carcinoma through stimulating the expression of uPA.</p>


Asunto(s)
Humanos , Carcinoma de Células Escamosas , Neoplasias de la Boca , Invasividad Neoplásica , Neoplasias de la Lengua , Activador de Plasminógeno de Tipo Uroquinasa
2.
West China Journal of Stomatology ; (6): 277-279, 2005.
Artículo en Chino | WPRIM | ID: wpr-300317

RESUMEN

<p><b>OBJECTIVE</b>To study the influence of thermochemotheraphy on the expression of HSP70 in maxillofacial squamous cell carcinoma.</p><p><b>METHODS</b>12 patients were treated with thermochemotheraphy twice a week, altogether 10 times. After 8 mg of Pingyangmycin infused, the patients were treated with microwave hyperthermia at 43 degrees C for 40 min. The part of carcinoma tissue was removed with surgical operations at before treatment and aftre five times of treatment. The expression of HSP70 in tumor cells was determined by SP immunohistochemcial method.</p><p><b>RESULTS</b>The expression of HSP70 in tumor cells was enhanced obviously by thermochemotherapy.</p><p><b>CONCLUSION</b>Special high expression of HSP70 in the tumor cells was induced by thermochemotherapy. With the antigen presenting action and other action, HSP70 have special antitumor effect.</p>


Asunto(s)
Humanos , Carcinoma de Células Escamosas , Proteínas HSP70 de Choque Térmico
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA