Studies on macrocyclic jatrophane diterpenes of Euphorbia kansui / 中国中药杂志

<p><b>OBJECTIVE</b>To study macrocyclic jatrophane diterpenes of Euphorbia kansui.</p><p><b>METHOD</b>The compounds were isolated and purified by various column chromatographic methods. Structures were elucidated by spectroscopic analyses.</p><p><b>RESULT</b>Three macrocyclic jatrophane diterpenes were isolated from E. kansui and were characterized as kansuinin D1 (1), kansuinin D (2), kansuinin A (3).</p><p><b>CONCLUSION</b>Kansuinin D1 (1) was a new compound.</p>

Chemical constituents in aerial part of Reineckea carnea / 中国中药杂志

<p><b>OBJECTIVE</b>To study the chemical constituents in the aerial part of Reineckea carnea.</p><p><b>METHOD</b>The compounds were isolated by extraction, silica gel, gel, and reversed-phase silica gel coloum chromatography, and high-performance liquid chromatography. The structures were identified by various spectroscopic methods including 1D and 2D NMR spectrum, MS, IR, etc.</p><p><b>RESULT</b>Six compounds were isolated and identified as 1alpha, 3beta-dihydroxy-5beta-pregn-16-en-20-one-3-O-beta-D-glucopyranoside (1), syringaresinol-beta-D-glucoside (2), sophoraflavone B (3), stigmast-5, 22-dien-3-O-beta-D-glucopyranoside (4), daucosterol (5), a-D-glucose (6).</p><p><b>CONCLUSION</b>Compound 1 was a new compound, coumpounds 2-6 were obtained from the plant for the first time.</p>

Chemical investingation of Chinese mangrove Sonneratia apetala II / 中国中药杂志

<p><b>OBJECTIVE</b>Isolation and structural elucidation of the constituents of China mangrove Sonneratia apetala.</p><p><b>METHOD</b>chromatography methods were used for isolation of compounds, spectroscopic methods were used for structural identifyication.</p><p><b>RESULT</b>seven known compounds named (+/-) symgaresinol, betulinic acid, lupeol, lupeone, stigmast-5-ene-3beta, 7alpha-diol, beta-alpha myrin hexadecaneate, physcoion were isolated.</p><p><b>CONCLUSION</b>these known compouns were unreported previously from this plant.</p>

Chemical constituents from the mangrove plant Ceriops tagal / 药学学报

<p><b>AIM</b>To investigate the secondary metabolites of the mangrove plant Ceriops tagal.</p><p><b>METHODS</b>Column chromatography techniques including HPLC were used for the separation and purification, and extensive spectral analysis including various 2D NMR spectra were employed for structure elucidation.</p><p><b>RESULTS</b>Nine compounds, namely, tagalsins A (1), ent-5alpha-dolabr-4 (18) -ene-15S,16-diol (2), squalene (3), betulinic acid (4), lup-20 (29) -en-3-on-28-oic acid (5), betulin (6), lup-20 (29) -en-3-on-28-ol (7), beta-sitosterol (8), n-hexacosanylferulate (9) were obtained. Of which 1 and 2 belong to dolabrane diterpene.</p><p><b>CONCLUSION</b>Compound 1 is a new compound, and 2 to 9 are isolated from this species for the first time.</p>

Chemical constituents from marine fungus Penicillium thomii / 药学学报

<p><b>AIM</b>To investigate the bioactive constituents from the mycelium of Penicillium thomii. Which isolated from Anemone collected in Qingdao beach.</p><p><b>METHODS</b>The constituents were separated by using various chromatography and the structures were identified on the basis of extensive spectral analysis.</p><p><b>RESULTS</b>Five compounds, namely penicillixanthone A (I), p-methylbenzolic acid (II), 1-O-hexadecanoyl-2-O-(9-octadecenoyl)-3-O-(9, 12-octadecadienoyl) glycerol (III), 5 alpha, 8 alpha-epidioxy-24 zeta-methylcholesta-6, 22-dien-3 beta-ol (IV) and 1, 6, 8-trihydroxyl-3-methyl-9, 10-anthracenedione (V), were isolated from the mycelium of Penicillium thomii.</p><p><b>CONCLUSION</b>Penicillixanthone A is a new compound, while the others are isolated from Penicillium thomii for the first time.</p>