Prevalence of food allergy in children under 2 years of age in three cities in China / 中华儿科杂志

<p><b>OBJECTIVE</b>To estimate the prevalence and clinical features of food allergy in children aged 0 - 2 years.</p><p><b>METHOD</b>From January to February, 2009 and January to May, 2010, all well-infants and young children between the age of 0 and 2 years attending routine health visits at the Department of Primary Child Care, in Chongqing, Zhuhai and Hangzhou were invited to participate in the study. Parents completed questionnaires and all children were skin prick tested (SPT) to a panel of 10 foods (egg white, egg yolk, cow's milk, soybean, peanut, wheat, fish, shrimp, orange and carrot). Based on the results of SPT and medical history, the subjects under went the suspected food elimination and oral food challenge under medical supervision. Food allergy was confirmed by the food challenge test.</p><p><b>RESULT</b>Totally 1687 children were recruited by the consent of their parents. Of 1687 children approached, 1604 (550 of Chongqing, 573 of Zhuhai and 481 of Hangzhou) fulfilled the study criteria for diagnosing food allergy. One hundred children were confirmed to have challenge-proven food allergy in 3 cities (40 of Chongqing, 33 of Zhuhai and 27 of Hangzhou). The prevalence of food allergy in 0-2 years old children in Chongqing was 7.3%, in Zhuhai was 5.8% and in Hangzhou was 5.5%. There was no significant difference in the prevalence of food allergy in children under 2 years among the three cities, and the average prevalence for food allergy in children under 2 years was 6.2%. Egg (3.0% - 4.4%) was the most common allergen, followed by cow's milk (0.83% - 3.5%), shrimp (0.17% - 0.42%) and fish (0.17% - 0.21%).</p><p><b>CONCLUSION</b>The prevalence of food allergy in 0 - 2 years old children in China was 5.5% - 7.3%. There was no significant difference in the prevalence of food allergy in children under 2 years of age among the three cities. Egg was the most common allergen, followed by cow's milk, shrimp and fish.</p>

Comparative evaluation of Hebei HIV-1 p24 kit for the detection of human immunodeficiency virus / 中华实验和临床病毒学杂志

<p><b>OBJECTIVE</b>To probe into the feasibility of screening anti-HIV compounds by using HIV-1 p24 detection kit made by Hebei Medical University.</p><p><b>METHODS</b>The sensitivity, reproducibility and efficacy of the Hebei p24 kit were evaluated compared with the commercially available Vironostika HIV-1 Antigen Microelisa System (Biomerieux).</p><p><b>RESULTS</b>Hebei p24 kit had high sensitivity and good reproducibility. In vitro screening demonstrated that there was no statistically significant difference (P greater than 0.05) between these two kits in assessing anti-HIV compounds.</p><p><b>CONCLUSION</b>Hebei p24 kit could be used as an easily affordable alternative method for detection of HIV-1 in screening anti-HIV compounds.</p>

Investigation on Variety of Blood Zinc,Copper,Iron,Calcium Levels in Children with Lead Poisoning / 实用儿科临床杂志

Objective To discuss the variety of blood zinc,copper,iron,calcium level in children of lead poisoning Methods The stratified - random sampling method was used. Five hundred and forty children were selected in the urban areas, the rural areas and the islands. We examined blood lead level and other elements levels of these children, and analyzed the changes of these elements levels on condition of lead poisoning. Results The blood zinc level of children with lead poisoning was (4. 93 ? 1 12) mg/L, it was significantly lower than that of children without lead poisoning( t = 2.282 P