RESUMEN
Background: Honey, as the most curative material, is used for healing majority of diseases. This study aimed at analyzing the role of honey and silver nano particles in changing blood biochemical factors in renal stone of male mice
Materials and methods: In this experimental study, 30 Albino male mice were randomly divided into 5 groups of 6 each, including healthy control, negative control received only water with 1% ethylen glycol, and 3 experimental groups received 15 ethylen glycol and 125mg/kg honey, 250 mg/kg honey and 125 ppm nano silver, respectively. After 30 days treatment, blood sampling was done via heart, and blood urea nitrogen [BUN], creatinine, and albumin were evaluated
Results: The findings showed that only in the group of 125 mg/kg honey, significant decrease and increases could be found in the amount of BUN [p<0.05] and ALB [p<0.05], respectively. However, compared to negative control group, there was not seen any significant difference in group of nano silver particles. Additionally, nothing was reported regarding the effects of these 3 groups on creatinine
Conclusion: It can be expected that honey, due to its strong antioxidant properties, will result in improvement of blood biochemical factor in kidney stone, while silver nano particles will cause increase in urine calcium oxalate and consequently lead to renal stone