Research progress of bone marrow edema-like lesions in knee osteoarthritis / 中国骨伤

Knee osteoarthritis-associated bone marrow edema-like lesions (KOA-BMLs) is a common MRI imaging feature, which is mainly manifested as abnormal bone marrow hyperintensity in subchondral bone on T2 imaging. The formation of KOA-BMLs may be related to the abnormality of lower limb force line and subchondral bone perfusion, and related histopathological studies showed that the remodeling of bone and bone marrow in these damaged areas was abnormally increased. In KOA patients, the size of BMLs can fluctuate or even disappear in a relatively short period of time, and was closely related to pain, subchondral bone cyst formation, and the progression of KOA. However, the current treatment methods for KOA-BMLs are limited, and there is no uniform guideline or expert consensus, mainly includingmedication, physical therapy and surgical treatment. This article reviews the research progress of the disease characteristics and treatment of KOA-BMLs in order to provide guidance for the clinical diagnosis and treatment of KOA-BMLs.

Retinal microcirculation detection technology and its clinical application / 国际眼科杂志(Guoji Yanke Zazhi)

@#Various eye diseases, especially retinal disease, can change the retinal microvascular. In addition, the disease such as cardiovascular disease that involves systemic vascular change also exist the change of retinal microcirculation. Therefore, the change of retinal microvascular system is important diseases index which not only an auxiliary diagnostic index for ocular diseases, but also an important index for the evaluation of systemic diseases. This paper briefly reviews the detection methods of retinal microcirculation examination and the clinical application of these methods.