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Rev. méd. Chile ; 141(4): 449-456, abr. 2013. ilus, tab
Artículo en Español | LILACS | ID: lil-680467

RESUMEN

Background: CT guided percutaneous biopsy of pulmonary lesions is a widely used technique. Aim: To evaluate the yield and complication rate of CT-guided percutaneous core biopsy of pulmonary lesions. Material and Methods: A retrospective study of 153 consecutive lung biopsies performed in a 7-yearperiod was undertaken. Patients and lesions characteristics were reviewed. The yield for the diagnosis of malignant and benign lesions and the complication rate were calculated. Lesion size and depth from the pleural surface were analyzed as potential predictive variables for occurrence of a false-negative diagnosis of malignancy. The final diagnosis was established by surgical biopsy of the lesion or clinical and imaging follow up. Results: The mean age of patients was 66 ± 14 years and 55% were mole. The final diagnosis of the lesion was malignant in 139 and benign in 14 cases (prevalence of malignancy 90.8%). For the diagnosis of malignancy, the overall yield ofthe biopsy was 91.5%o with a sensitivity of 90.6%>. A specific diagnosis of benign lesions was obtained in 5 out ofl4 biopsies (35%). We did not identify an association between the lesion size or depth and the rate of false-negative diagnosis of malignancy. The pneumothorax rate was 13.7%o (n = 21) and eight (38%) required drainage. The average lesion depth of patients that had a pneumothorax was significant greater than the cases without the complication. No major bleeding complications occurred. Conclusions: Percutaneous CT-guided cutting needle biopsies of pulmonary lesions have an excellent diagnostic accuracy for malignant pulmonary lesions, at a low complication rate.


Asunto(s)
Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Niño , Preescolar , Femenino , Humanos , Masculino , Persona de Mediana Edad , Adulto Joven , Biopsia con Aguja/métodos , Enfermedades Pulmonares/patología , Pulmón/patología , Tomografía Computarizada por Rayos X/métodos , Biopsia con Aguja/efectos adversos , Enfermedades Pulmonares , Neoplasias Pulmonares/patología , Neoplasias Pulmonares , Pulmón , Valor Predictivo de las Pruebas , Radiografía Intervencional/métodos , Estudios Retrospectivos , Sensibilidad y Especificidad , Tomografía Computarizada por Rayos X/efectos adversos
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