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1.
Journal of Korean Neurosurgical Society ; : 24-30, 2012.
Artículo en Inglés | WPRIM | ID: wpr-145567

RESUMEN

OBJECTIVE: This study was conducted to assess the clinical significance of traumatic brain stem injury (TBSI) reflected on Glasgow Coma Score (GCS) and Glasgow Outcome Score (GOS) by various clinical variables. METHODS: A total of 136 TBSI patients were selected out of 2695 head-injured patients. All initial computerized tomography and/or magnetic resonance imaging studies were retrospectively analyzed according to demographic- and injury variables which result in GCS and GOS. RESULTS: In univariate analysis, mode of injury showed a significant effect on combined injury (p<0.001), as were the cases with skull fracture on radiologic finding (p<0.000). The GCS showed a various correlation with radiologic finding (p<0.000), mode of injury (p<0.002), but less favorably with impact site (p<0.052), age (p<0.054) and skull fracture (p<0.057), in order of statistical significances. However, only GOS showed a definite correlation to radiologic finding (p<0.000). In multivariate analysis, the individual variables to enhance an unfavorable effect on GCS were radiologic finding [odds ratio (OR) 7.327, 95% confidence interval (CI)], mode of injury (OR; 4.499, 95% CI) and age (OR; 3.141, 95% CI). Those which influence an unfavorable effect on GOS were radiologic finding (OR; 25.420, 95% CI) and age (OR; 2.674, 95% CI). CONCLUSION: In evaluation of TBSI on outcome, the variables such as radiological finding, mode of injury, and age were revealed as three important ones to have an unfavorable effect on early stage outcome expressed as GCS. However, mode of injury was shown not to have an unfavorable effect on late stage outcome as GOS. Among all unfavorable variables, radiological finding was confirmed as the only powerful prognostic variable both on GCS and GOS.


Asunto(s)
Humanos , Encéfalo , Tronco Encefálico , Coma , Imidazoles , Imagen por Resonancia Magnética , Análisis Multivariante , Estudios Retrospectivos , Fracturas Craneales
2.
Korean Journal of Cerebrovascular Surgery ; : 126-134, 2007.
Artículo en Inglés | WPRIM | ID: wpr-151512

RESUMEN

OBJECTIVES: Shunt-dependent hydrocephalus is the major sequela after subarachnoid hemorrhage (SAH) and this continues to be a major source of morbidity for these patients. The prevalence and risk factors are not clear, despite the significant clinical and basic science research that's been done. We analyze the risk factors of shunt-dependent hydrocephalus such as the clinical and radiological parameters, the treatment modality and the peri-operative preparation. METHODS: We collected data on 475 patients with aneurysmal SAH and who were admitted to our hospital between January 1996 and January 2005. We retrospectively analyzed the age, gender, Hunt-Hess grade, Fisher grade, hypertension, intraventricular hemorrhage (IVH), rebleeding, vasospasm, location of aneurysm, treatment modality, timing of surgery, lumbar drainage, external ventricular drainage (EVD) and the prognosis as risk factors. RESULTS: 22.1% (105/475) of the aneurysmal SAH patients developed shunt-dependent hydrocephalus. Univariate analysis revealed that the patient's age, Hunt Hess grade, IVH, rebleeding, vasospasm, location of aneurysm, timing of operation, lumbar drainage, EVD and the prognosis had statistically significant correlation with the development of shunt-dependent hydrocephalus (p<0.05). Through multivariate regression analysis, the aneurysms located in the posterior circulation, use of lumbar drainage and the cases with acute hydrocephalus showed a high prevalence of shunt-dependent hydrocephalus. CONCLUSION: Among the numerous factors, only lumbar drainage was a partially controllable factor. Further analysis of the clinical factors associated with CSF drainage and re-evaluation of the indications for drainage are needed.


Asunto(s)
Humanos , Aneurisma , Drenaje , Hemorragia , Hidrocefalia , Hipertensión , Prevalencia , Pronóstico , Estudios Retrospectivos , Factores de Riesgo , Hemorragia Subaracnoidea
3.
Korean Journal of Cerebrovascular Surgery ; : 238-242, 2007.
Artículo en Inglés | WPRIM | ID: wpr-167949

RESUMEN

OBJECTIVE: The authors investigated the clinical and radiographic characteristics of patients who exhibited contrast extravasation on initial computed tomographic angiography (CTA) and assessed the its association with hematoma expansion. METHODS: Ninety six patients who were diagnosed with intracerebral hemorrhage and who received CTA within 12 hours from initial onset of symptoms and who received a follow up brain CT within 48 hours from the initial CTA between April 2004 and March 2007 were retrospectively assessed. Contrast extravasation was defined as the presence of high-density material within the hematoma. Patients were classified into the extravasation and no extravasation groups. Clinical and radiographic variables were compared between the two groups. RESULTS: Fifteen patients (19%) demonstrated presence of extravasation on initial CTA. A significantly higher rate of hematoma expansion was seen in the extravasation group compared to the non extravasation group (47% vs 17%, p=0.027). Mean time from onset of symptoms to initial CTA was significantly shorter in the extravasation group (3.5+/-1.3 hours vs 7.6+/-2.5 hours, p0.001). CONCLUSIONS: Earlier detection of extravasation using CTA may help in identifying possibly life threatening complications caused by hematoma expansion. However, a larger prospective cohort is warranted to validate this result.


Asunto(s)
Humanos , Angiografía , Encéfalo , Hemorragia Cerebral , Estudios de Cohortes , Estudios de Seguimiento , Hematoma , Estudios Retrospectivos
4.
Korean Journal of Cerebrovascular Surgery ; : 216-220, 2007.
Artículo en Inglés | WPRIM | ID: wpr-34796

RESUMEN

Posttraumatic high-flow communications between the intracavernous internal carotid artery (ICA) and the cavernous sinus may give rise to two different pathological entities. A connection from the intracavernous ICA system can theoretically connect with two different structures; the vein of the plexus (CCF) or the perivascular bare spaces between the veins (pseudoaneurysm). A CCF and a pseudoaneurysm can be present in the same patient. A 24-year-old man was admitted to our hospital due to sudden mental deterioration. Carotid angiography revealed a CCF, which had occurred after a trauma 5 years earlier, associated with left visual disturbance and skull base fractures. The treatment of choice was permanent coil occlusion of the intracavernous ICA at the level of the lesion. The collateral circulation was evaluated before the endovascular treatment using a balloon test occlusion (BTO). During the BTO, adequate collateral circulation was defined as symmetric angiographic filling of both hemispheres. A continuous neurological examination was performed during the procedure. The follow-up angiography showed a persistent aneurysm occlusion. We report our experience of the successful endovascular treatment of combined lesions with a review of the relevant literature.


Asunto(s)
Humanos , Adulto Joven , Aneurisma , Aneurisma Falso , Angiografía , Arteria Carótida Interna , Seno Cavernoso , Circulación Colateral , Fístula , Estudios de Seguimiento , Examen Neurológico , Base del Cráneo , Venas
5.
Korean Journal of Cerebrovascular Surgery ; : 163-171, 2006.
Artículo en Coreano | WPRIM | ID: wpr-166219

RESUMEN

OBJECTIVE: Our goal was to evaluate the usefulness of CT perfusion (CTP) in early detection of the post operative cerebral ischemia, alteration of treatment modality and patient prognosis in cerebral aneurysm patients. METHODS: 24 patients who underwent either surgical operation or endovascular coiling for ruptured aneurysms were selected. All patients undertook an angiogram, conventional CT, and CTP scan immediately following surgical operation or endovascular coiling. All patients performed a CT 2 weeks after treatment to evaluate possible development of a cerebral infarction. Postoperative CT results of patients with abnormal postoperative CTP scan findings were compared, and these results were compared with the CT results and clinical symptoms of patients who developed infarction or not. RESULTS: Of the 24 patients evaluated, 11 patients showed abnormal findings on CTP. 9 patients were diagnosed with cerebral infarction through a CT scan done 2 weeks after treatment; all exhibited abnormal CTP results immediately after treatment. Abnormal CTP findings were divided into two groups; patients with abnormal CBF and MTT maps, but with normal CBV maps, and patients with abnormal CBF, CBV and MTT maps. A correlation was seen between abnormality on CBV maps and cerebral infarction. Patients with abnormal CTP findings also exhibited poorer prognostic value. CONCLUSION: Postoperative CTP in ruptured aneurysm patients is a very useful and objective tool in evaluating abnormal cerebral hemodynamics. The CBV map of CTP is the most precisely predictable value of postoperative patient's status and alteration of treatement modality.


Asunto(s)
Humanos , Aneurisma Roto , Isquemia Encefálica , Infarto Cerebral , Citidina Trifosfato , Hemodinámica , Infarto , Aneurisma Intracraneal , Perfusión , Pronóstico , Tomografía Computarizada por Rayos X
6.
Journal of Korean Neurosurgical Society ; : 20-25, 2006.
Artículo en Inglés | WPRIM | ID: wpr-67204

RESUMEN

OBJECTIVE: The authors analyze prospectively the result of transcranial doppler(TCD) in normal pressure hydrocephalus and compared its cerebral blood flow parameters to radionuclide cerebrospinal fluid(CSF) flow study, postoperative brain computed tomography(CT) findings and clinical outcome, and studied the relationship betweeen cerebral hemodynamics and clinical performance. METHODS: Twenty five patients with hydrocephalus undertook pre- and post-operative TCD but only preoperative CSF flow study was performed. Mean flow velocity(Vm), pulsatility index(PI) and resistance index(RI) were assessed through TCD and changes in ventricle size and cortical gyral atrophy were checked through brain CT. RESULTS: Postoperative hydrocephalus showed an increase in Vm(ACA P=0.037, MCA P=0.034), decrease in PI(ACA P=0.019, MCA P=0.017) and decrease in RI (ACA P=0.017, MCA P=0.021) compared to preoperative TCD parameters in the postoperative improvement group. In the postoperative improvement group, postoperative TCD parameters correlated with CSF flow study grade (Vm: R2=-0.75, PI: R2=0.86, RI: R2=0.78) and ventriculocranial ratio change correlated with PI change (R2=0.73). The convexity gyral atrophy and initial TCD parameters showed close relationship to outcome. CONCLUSION: PI and RI can be used as an indicator of post operative prognosis, and with the addition of CSF flow study values, can also be used as a tool to predict pre-op and post-op patient status and successful shunt surgery.


Asunto(s)
Humanos , Atrofia , Encéfalo , Líquido Cefalorraquídeo , Hemodinámica , Hidrocefalia , Hidrocéfalo Normotenso , Pronóstico , Estudios Prospectivos
7.
Korean Journal of Cerebrovascular Surgery ; : 48-53, 2005.
Artículo en Coreano | WPRIM | ID: wpr-96477

RESUMEN

OBJECT: This study is designed to estimate the clinical usefulness of perfusion computed tomography (perfusion CT) as an easily accessible tool to evaluate cerebral blood flow (CBF) in patients with aneurysmal subarachnoid hemorrhage. METHOD: Twenty patients with aneurysmal spontaneous subarachnoid hemorrhage who underwent either aneurysmal neck clipping or interventional coil embolization and who also had taken transcranial doppler study and perfusion CT were included as study group. And as a control group, fifteen patients without neurologic deficit were studied with the same devices. We compared the cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT) from obtained perfusion CT with the results of transcranial doppler and clinical course. RESULTS: CBF parameters of perfusion CT in control group showed close accordance with those values of reported xenon CT and positron emission tomography data. In doppler study, the blood flow velocity was higher in cases with vasospasm than without it (p=0.027). There showed significant relationship between vasospasm and perfusion CT parameters, as decrease in CBF (p=0.061) and increase in MTT (p=0.013). Perfusion CT parameters were closely correlated with TCD parameters in clinical vasospasm as reverse correlation in CBF (R2=0.45) and positive in MTT (R2=0.58). CONCLUSION: The cerebral blood flow parameters of Perfusion CT showed reliable and accurate values in control group. The perfusion CT and TCD can be used as easily accessible non-invasive tools to evaluate cerebral blood flow parameters in clinical settings of patients with aneurysmal subarachnoid hemorrhage.


Asunto(s)
Humanos , Aneurisma , Velocidad del Flujo Sanguíneo , Volumen Sanguíneo , Embolización Terapéutica , Cuello , Manifestaciones Neurológicas , Perfusión , Tomografía de Emisión de Positrones , Hemorragia Subaracnoidea , Xenón
8.
Korean Journal of Cerebrovascular Surgery ; : 54-60, 2005.
Artículo en Coreano | WPRIM | ID: wpr-96476

RESUMEN

OBJECTIVES: The aim of this study are clinical application of perfusion computed tomography (perfusion CT) in hydrocephalus and comparison its cerebral blood flow parameters with transcranial doppler (TCD) and clinical outcome. METHOD: 25 patients with hydrocephalus took pre- and postoperative perfusion CT and TCD. 15 patients without neurologic deficit were also examined with same protocol as a control. Blood flow parameters of perfusion CT, such as cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT) were analyzed according to clinical status and postoperative outcome. So did the TCD parameters, mean flow velocity (mFv) and pulsatility index (PI) with regard to clinical outcome. RESULTS: Perfusion CT parameters of the hydrocephalus showed decrease in CBF (gray matter P=0.035, periventricular region P=0.042) and increase in MTT (gray matter P=0.039, periventricular region P=0.045) compared to control. In postoperative improvement group, there noted reversal of perfusion parameters close to those of the control. TCD parameters showed increase in mFv (P=0.047), and decrease in PI (P=0.042) in cases with improvement. CONCLUSION: Perfusion brain CT and TCD can used as clinically useful tools to predict the postoperative outcome on hydrocephalus.


Asunto(s)
Humanos , Volumen Sanguíneo , Encéfalo , Hidrocefalia , Manifestaciones Neurológicas , Perfusión
9.
The Korean Journal of Parasitology ; : 201-203, 2004.
Artículo en Inglés | WPRIM | ID: wpr-177057

RESUMEN

A survey was conducted to determine the extent of intestinal parasite infection in Bat Dambang, Cambodia in March 2004. A total of 623 fecal specimens was collected from kindergarten and schoolchildren and examined using the formalin-ether sedimentation technique. The overall infection rate of intestinal parasites was 25.7% (boys, 26.2%; girls, 25.1%), and the infection rates of intestinal helminthes by species were as follows: Echinostoma sp. 4.8%, hookworm 3.4%, Hymenolepis nana 1.3%, and Rhabditis sp. 1.3%. The infection rates of intestinal protozoa were; Entamoeba coli 4.8%, Giardia lamblia 2.9%, Iodamoeba butschlii 1.4%, Entamoeba polecki 1.1%, and Entamoeba histolytica 0.8%. There were no egg positive cases of Ascaris lumbricoides or Trichuris trichiura. All children infected were treated with albendazole, praziquantel, or metronidazole according to parasite species. The results showed that intestinal parasites are highly endemic in Bat Dambang, Cambodia.


Asunto(s)
Adolescente , Animales , Niño , Femenino , Humanos , Masculino , Factores de Edad , Cambodia/epidemiología , Heces/parasitología , Helmintiasis/epidemiología , Helmintos/aislamiento & purificación , Parasitosis Intestinales/epidemiología , Eucariontes/aislamiento & purificación , Infecciones por Protozoos/epidemiología
10.
Journal of Korean Neurosurgical Society ; : 106-108, 2004.
Artículo en Inglés | WPRIM | ID: wpr-184464

RESUMEN

Third cranial nerve palsy may indicate the presence of an intracranial aneurysm, most commonly in the posterior communicating artery. The effect of endovascular management of posterior communicating artery aneurysms on recovery from third cranial nerve palsy is not well documented. We report two patients with third cranial nerve palsy caused by posterior communicating artery aneurysms. Endovascular treatment resulted in subsiding of ptosis within two weeks. Resolution of extraocular muscle function occurred within one to three months after treatment. Endovascular treatment, which has recently been introduced into neurosurgical practice, is effective in preventing aneurysmal rupture, and in eliminating manifestations due to mass effects.


Asunto(s)
Humanos , Aneurisma , Arterias , Aneurisma Intracraneal , Nervio Oculomotor , Parálisis , Rotura
11.
Journal of Korean Neurosurgical Society ; : 465-471, 2004.
Artículo en Coreano | WPRIM | ID: wpr-87700

RESUMEN

OBJECTIVE: We report a retrospective investigation of the prognostic value of bcl-2 and bax expression, and Ki-67 proliferative index in 42 astrocytic tumors. METHODS: We classified the astrocytic tumors and reviewed the clinical information and survival time. The sections were taken from surgically resected paraffin-embedded tissue and performed immunohistochemical stains for bcl-2, bax and Ki-67. RESULTS: The immunohistochemical stain for bcl-2 revealed a positivity in only two(4.76%) among forty-two cases. The immunostain for bax was positive in 35 cases(83.3%). However, the correlation between bcl-2 & bax expression and age, sex, tumor location, size, and histologic grade was not found. By Kaplan-Meier analysis, bcl-2 & bax expression and survival time in astrocytic tumors was no significance in log rank test(p>0.05). There were prognostic values between Ki-67 LI and histologic grade and between Ki-67 LI and survival time, respectively(p<0.05). CONCLUSION: Bcl-2 and bax are not significant, whereas Ki-67 LI is suggested as a significant prognostic factor, associated with histologic grade and survival time of astrocytic tumors.


Asunto(s)
Colorantes , Estimación de Kaplan-Meier , Pronóstico , Estudios Retrospectivos
12.
Journal of Korean Neurosurgical Society ; : 297-301, 2004.
Artículo en Coreano | WPRIM | ID: wpr-54431

RESUMEN

OBJECTIVE: TA retrospective study is performed on 28 patients with primary intraventricular hemorrhage(PIVH) to examine the outcome and prognostic factors associated with this disorder. METHODS: Clinical data collected between 1998 and 2002 was used in the present study. The outcomes of these patients were compared by age, etiology, initial Glasgow Coma Score(GCS), Graeb's score, ventriculocranial ratio(VCR), hemorrhagic dilation of the third ventricle, and hemorrhagic dilation of the fourth ventricle. The Glasgow Outcome Scale(GOS) at discharge was used for the comparison of outcomes. RESULTS: The mean age of these patients was 48.4+/-17.4 years. The underlying causes of PIVH were hypertension(53.6%), moyamoya disease(17.9%), arteriovenous malformation(10.7%), cerebral aneurysm(7.1%), and unknown(10.7%). The age and etiology were not correlated with outcome. Patients with a GCS of 13-15 showed a good outcome in 90.5%(p or =0.23) showed a poor outcome in 64.3%(p<0.05). Patients with a Graeb's score of 9-12 showed a poor outcome in 87.5%(p<0.05). Those with hemorrhagic dilatation of the third ventricle showed a poor outcome in 80.0%, and those with hemorrhagic dilatation of the fourth ventricle showed a poor outcome in 85.7%(p<0.05). The overall mortality rate was 17.9%. CONCLUSION: Low initial GCS, high Graeb's score, high VCR, and hemorrhagic dilatation of the third ventricle or the fourth ventricle are correlated with poor outcome in PIVH.


Asunto(s)
Humanos , Coma , Dilatación , Cuarto Ventrículo , Hemorragia , Mortalidad , Estudios Retrospectivos , Tercer Ventrículo
13.
Journal of Korean Neurosurgical Society ; : 142-148, 2003.
Artículo en Coreano | WPRIM | ID: wpr-207740

RESUMEN

OBJECTIVE: This study is designed to evaluate the therapeutic effects and prognostic factors for barbituate coma therapy(BCT)in severe and refractory vasospasm following subarachnoid hemorrhage. METHODS: Barbiturate coma therapy was used in 18 patients with severe and refractory vasospasm in spite of "3-H therapy" and intra-arterial papaverine infusion. The authors analyzed the clinical parameters including Glasgow Coma Scale(GCS), electroenceplographic finding, and brain computerized tomography(CT) scan findings in relation to outcome at discharge. RESULTS: Among 18 patients, burst suppression pattern could be obtained in 17. In cases with good outcome, the duration elapsed from coma to drowsiness after BCT was 14.09+/-5.82 days and GCS score at this time was significant in the prediction of final outcome(p<0.05). Patients with ideal burst suppression pattern attainable more than 24 to 48 hours showed good outcome in 81.8%(p<0.05). The group that showed focal low density in the brain CT scan taken before BCT fared better prognosis compared with that of multifocal or diffuse low density(p<0.05), and patients with resolution of perimesencephalic cistern effacement on follow-up brain CT scan taken 48 hours after BCT showed better prognosis(p<0.05). Overall, 72.2% showed improvement of GCS score by 2 or more, and good outcome was noted in 50%. CONCLUSION: The barbiturate coma therapy seems to have a beneficial therapeutic effect on severe and refractory vasospasm and can be considered as a useful therapeutic modality.


Asunto(s)
Humanos , Encéfalo , Coma , Estudios de Seguimiento , Papaverina , Pronóstico , Fases del Sueño , Hemorragia Subaracnoidea , Tomografía Computarizada por Rayos X
14.
Journal of Korean Neurosurgical Society ; : 616-619, 2002.
Artículo en Coreano | WPRIM | ID: wpr-220037

RESUMEN

The diagnosis and appropriate management of blunt abdominal trauma including retroperitoneal hematoma associated head injury is difficult. In our case, psoas muscle hematoma was revealed during the evaluation of fever. Psoas muscle hematoma most commonly results secondarily from coagulation defect or from retroperitoneal bleeding into the psoas sheath. The presenting signs and symptoms of this case are hypotension and anemia. Pain is also present in the back or abdomen. If it is associated with head injury and not presented massive hemorrhage, the actual diagnosis is not easy. The appropriate management depends on a careful initial evaluation including suspicion of physician, repetitive physical examination, the timely use of diagnostic procedures.


Asunto(s)
Abdomen , Anemia , Traumatismos Craneocerebrales , Diagnóstico , Fiebre , Cabeza , Hematoma , Hemorragia , Hipotensión , Examen Físico , Músculos Psoas
15.
Journal of Korean Neurosurgical Society ; : 564-568, 2002.
Artículo en Coreano | WPRIM | ID: wpr-224263

RESUMEN

OBJECTIVE: The elderly population is rapidly growing, and the population over age 65 is expected to increase. To evaluate factors that determine recovery in this population, we report a clinical analysis of 77 elder patients of mild head trauma over 65 years of age. METHODS: The medical records were reviewed retrospectively for 77 head-injured patients aged 65 to 85 years who were admitted to our institution between March, 1995 and December, 1999. The outcome was compared with age, sex, Glasgow Coma Scale score, and radiologic characteristics. RESULTS: As in all age groups, males predominated and motor vehicle accidents accounted for a highest proportion(35%). Of the traffic accidents, pedestrian injuries were more common. The single most common lesion was subdural hematoma. The initial radiologic findings were not correlated with outcome. The GCS score was statistically correlated with prognosis. Sixty-one patients(79.2%) had favorable outcome. Ten of seventy-seven patients(13%) died whereas cerebral injury accounted for 5 deaths. Non-cerebral causes of death were composed of pneumonia, multi-organ failure and sepsis. The mean hospitalization was 52.3+/-12.6 days. CONCLUSION: The mortality rate after injury is higher in elderly patients. It is therefore the factors of intracranial and extracranial cause which influence survival and outcome be carefully treated. Neurologic deficits, even though mild, are the risk factor of poor prognosis in the elderly. Earlier identification of risk and aggressive support may be needed for decreasing the morbidity and the mortality in the elderly.


Asunto(s)
Anciano , Humanos , Masculino , Accidentes de Tránsito , Causas de Muerte , Traumatismos Craneocerebrales , Escala de Coma de Glasgow , Cabeza , Hematoma Subdural , Hospitalización , Registros Médicos , Mortalidad , Vehículos a Motor , Manifestaciones Neurológicas , Neumonía , Pronóstico , Estudios Retrospectivos , Factores de Riesgo , Sepsis
16.
Journal of Korean Neurosurgical Society ; : 448-452, 2002.
Artículo en Coreano | WPRIM | ID: wpr-80460

RESUMEN

OBJECTIVE: The purpose of this study is to evaluate the findings of magnetic resonance(MR) perfusion study and relation with the prognosis in patients of head trauma. METHODS: Forty-two consecutive patients with head trauma were evaluated and the findings of brain computed tomography(CT) and MR image were compared with MR perfusion study. We classified perfusion MR findings into 5 categories and correlated with the prognosis. RESULTS: In all 42 patients with head trauma, 38 cases(90.5%) showed new lesions of abnormal perfusion pattern in MR perfusion study compared to CT and conventional MR image. Causes of the trauma were motor vehicle accident(73.8%) falling(16.7%), and blows to the head(7.1%) in order of frequency. The cumulative prevalent sites of focal abnormalities were frontal lobe in 11 cases(39.3%), basal ganglia and thalamus 9 cases(32.1%), temporal lobe 3 cases(10.7%) and parietal lobe 3 cases(10.7%) and occipital lobe 1 case(3.6%) and cerebellum 1 case(3.6%). The pattern of abnormalities in MR perfusion study were focal type in 18 cases(42.8%), diffuse type 18 cases(42.8%), mixed type 4 cases(9.5%). MR perfusion findings showed statistically significant correlation with initial Glasgow Coma Scale score and Glasgow Outcome Scale score(p<0.05). CONCLUSION: The patterns of perfusion MR abnormality show significant correlation with the prognosis. Further study is mandatory to define the meaning of perfusion defect area and clinical significance.


Asunto(s)
Humanos , Ganglios Basales , Encéfalo , Cerebelo , Traumatismos Craneocerebrales , Lóbulo Frontal , Escala de Coma de Glasgow , Escala de Consecuencias de Glasgow , Cabeza , Vehículos a Motor , Lóbulo Occipital , Lóbulo Parietal , Perfusión , Pronóstico , Lóbulo Temporal , Tálamo
17.
Journal of Korean Neurosurgical Society ; : 133-138, 2002.
Artículo en Coreano | WPRIM | ID: wpr-93604

RESUMEN

OBJECTIVE: The authors analyze the incidence, etiological and prognostic factors between contralateral and ipsilateral delayed epidural hematoma after evacuation of initial hematoma and to formulate recommendations for early detection of evolving hematoma and improvement of outcome. METHODS: Between July 1997 and December 1999, 417 patients underwent craniotomy at department of neurosurgery to evacuate an acute posttraumatic intracranial hematoma. Analysis of these clinical and neuroradiologic data showed that we underwent a second operation on 24 patient(5.8%) for removal of delayed epidural hematoma. In 10(2.4%) of these patients the second operation was undertaken to evacuate a new hematoma that had developed at a contralateral side from the initial hematoma. In 14 patients(3.4%), the second operation was to remove a epidural hematoma at the same site as the first craniotomy. RESULTS: 24 patients were divided into two groups. In Group A, 10 patients who developed contralateral delayed epidural hematoma were 31.5 years(11-61) of age and had skull fracture at the site of delayed epidual hematoma formation. Two of these patients revealed severe brain swelling during the evacuation of acute subdural hematoma. Eight of them were diagnosed within 24 hours after craniotomy through immediately postoperative computed tomography scan. In Group B, 14 patients who developed ipsilateral epidural hematoma were 56.1 years(27-75) of age. Six of them had hemorrhagic tendency related to past medical history. Eleven of these patients were associated with thrombocytopenia and consumptive coagulopathy when required second operation. Twelve patients were diagnosed within 48-72 hours after craniotomy due to clinical deterioration or failure to improve. There was no significant difference in outcome between two groups. CONCLUSION: The authors sought differential factors between contralateral and ipsilateral delayed epidural hematoma. Delayed epidural hematoma after craniotomy may need an urgent operation or lead to serious complication or disability. Postoperative computed tomography scan, intracranial pressure monitoring and repeat computed tomography scan within 72 hours of injury are strongly recommended in these cases, especially after decompression of cranial cavity.


Asunto(s)
Humanos , Edema Encefálico , Craneotomía , Descompresión , Hematoma , Hematoma Subdural Agudo , Incidencia , Presión Intracraneal , Neurocirugia , Fracturas Craneales , Trombocitopenia
18.
The Korean Journal of Parasitology ; : 153-156, 2002.
Artículo en Inglés | WPRIM | ID: wpr-99427

RESUMEN

A survey was made to find the extent of intestinal parasite infection in Kampongcham, Cambodia in February 2002. A total of 251 fecal specimens were collected from Tonlebat primary school children and examined by formalin-ether sedimentation technique. The overall infection rate of intestinal parasite was 54.2% (males, 57.3%; females, 50.8%). The infection rate of intestinal helminths by the species were as follows: Ascaris lumbricoides 26.3%, Echinostoma sp. 15.6%, hookworm 6.4%, Opisthorchis sp. 4.0%, Rhabditis sp. 2.4%, and Trichuris trichiura 0.4%. The infection rate of intestinal protozoa were as follows: E. coli 7.6%, G. lamblia 3.2%, I. butschlii 3.2%, and E. histolytica 0.8%. More than two different kinds of parasites were found in 16.7% of the stool samples. All the children infected were treated with albendazole, praziquantel and metronidazole according to parasite species. The results showed that intestinal parasites are highly endemic in this area.


Asunto(s)
Animales , Niño , Femenino , Humanos , Masculino , Factores de Edad , Antiparasitarios/uso terapéutico , Cambodia/epidemiología , Heces/parasitología , Parasitosis Intestinales/tratamiento farmacológico , Intestinos/parasitología , Parásitos/aislamiento & purificación , Prevalencia , Instituciones Académicas/estadística & datos numéricos
19.
Journal of Korean Neurosurgical Society ; : 1182-1186, 2001.
Artículo en Coreano | WPRIM | ID: wpr-41443

RESUMEN

OBJECTIVES: MR fluid-attenuated inversion recovery(FLAIR) image uses paired long inversion time and relaxation time that nulls the signal from CSF. With nulling of the CSF long echo time readout could be used to increase T2-weighting, hence improving the conspicuousness of most tissue lesions without the deleterious effects of CSF artifact seen on T2 weighted sequence. We examed the usefulness of FALIR image in the diagnosis of mild head injury. METHODS: A total of 38 patients with mild head injury were examined by FLAIR image. We compared those images with CT scan and T1, T2-weighted images. Careful observation of MR images were done by two well-trained neuroradiologists. Each image was compared for conspicuousness and detectability of traumatic lesions might have shown abnormal signal intensities. The Wilcoxon signed ranks test was used for statistical evaluation. RESULTS: The FLAIR image was significantly more sensitive than those of other images(p<0.001). T2 FFE(Fast Field Echo) image was more useful for detection of small petechial hemorrhages. CONCLUSION: FLAIR image is considered to be more sensitive than those of conventional MR images in the evaluation of mild head injuries.


Asunto(s)
Humanos , Artefactos , Traumatismos Craneocerebrales , Diagnóstico , Cabeza , Hemorragia , Relajación , Tomografía Computarizada por Rayos X
20.
Journal of Korean Neurosurgical Society ; : 642-646, 2001.
Artículo en Coreano | WPRIM | ID: wpr-77313

RESUMEN

A 12-years-old female admitted to the hospital with the complaint of pain on the right upper chest area which persisted about 1 month prior to admission. Cafe-au-lait spots of various size laying on a whole body and freckling on the axilla were found on physical examination. A huge mass was found on the plain chest X-ray and on chest MRI. The mass encroached thoracic spine, posterior rib, back muscles, and then into the neural canal and compressed thoracic spinal cord. On the 5th day of hospitalization, the patient complained tingling on the both legs and 2 days later, monoparesis on the right leg. Open thoracotomy and decompressive laminectomy was done to remove mass. Pathologic reports confirmed rhabdomyosarcoma, embryonal type.


Asunto(s)
Femenino , Humanos , Axila , Músculos de la Espalda , Manchas Café con Leche , Hospitalización , Laminectomía , Pierna , Imagen por Resonancia Magnética , Mediastino , Tubo Neural , Paresia , Examen Físico , Rabdomiosarcoma , Rabdomiosarcoma Embrionario , Costillas , Compresión de la Médula Espinal , Médula Espinal , Columna Vertebral , Toracotomía , Tórax
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