Head and neck cancer association to CIAP-2 expression due to human papillomavirus-16 [HPV-16] infection

It was relevant to assess the impact of a HPV-16 [human papillomavirus-16] which is a high-risk genotype on head and neck cancers and its relation to CIAP-2 expression [Cellular Inhibitor of apoptosis-2]. Tissue samples were taken from patients diagnosed as head and neck cancer. All samples were subjected to qualitative polymerase chain reaction [PCR] analysis for HPV, qualitative and semi-quantitative reverse transcription polymerase chain reaction [RT-PCR] of CIAP-2. There was a significant association between HPV-16 and CIAP2 positivity and head and neck tumors. CIAP-2 expression in malignant tissues was highly associated with HPV-16 infection at sensitivity 73.9% and absolute specificity

Maxillary sinus mucopyoceles

Maxillary sinus mucopyoceles are rarely seen, and their origin has been a subject of much controversy. Three cases are reported here in: whatever the cause of the mucopyoceles, the best treatment is a Caldwell-Luc's operation

Unusual sites of fungal infection

Isolated fungal infection is unusual head and neck infection. Three rare sites of infection are reported, first is a case of isolated sellar with para-cellar extension. A second case of pterygopalatine fossa infection, and a 3rd case of pituitary fungal granuloma. Diagnosis and management of these conditions are described. Aggressive surgical debridment to ensure good drainage and antifungal medical treatment [Ketoconazole. 200 mg] were advocated for treatment of fungal infection

Reconstruction of the palate using pectoralis major myocutaneous flap

The functional deformity following removal of the maxilla is considerable. Rehabilitation used to be very difficult with prosthesis or traditional flaps. Pectoralis major myocutaneous flaps have been used for reconstruction following hemi maxillectomy. Three cases are presented to illustrate the use of pectoralis major myocutoneous flap following partial removal of the maxillae at a Le-Fort I Level

Lyophilized dura for tympanic membrane replacement

110 patients with chronic suppurative otitis media, were subjected for different types of tympanoplasty. 50 patients underwent only myringoplasty, while the other 60 patients were treated with wide access tympanoplasty in whom 30 cases were done as first stage procedure, and in the other 30 cases ossiculoplasty using either TORP or PORP was done in the same sitting. For all the cases, allograft dura was used for drum head replacement. Results were evaluated as regards anatomical and functional outcomes. Allograft dura seems to be a satisfactory material for tympanic membrane replacement especially in open cavities and in the presence of infection, but its use is not recommended when another foreign material is used as TROP or PORP