Cases of screw-retained implant prosthesis in the anterior maxilla through multidisciplinary approach, including orthodontic teeth alignment / 대한치과보철학회지

The labio-palatal location of the implant in the maxillary anterior region is one of the important factors affecting the aesthetics of the implant prosthesis. However, the thin labial bone of maxilla could be absorbed in significant amounts after extraction of the teeth, which makes the implant be placed on the palatal side rather than the ideal location. In fact, in the cases of maxillary central incisor loss, UCLA was used for prosthetic restoration of palatally placed implant. In addition, with multidisciplinary treatment, GBR (Guided Bone Regeneration) was performed for compensating the absorbed alveolar bone and adjacent anterior tooth were aligned. Definitive restoration was performed after confirming aesthetic recovery of the gingiva with sufficient provisional restoration period. There were satisfactory results of functional and esthetic recovery of tooth loss through implant prosthesis.

Poly-L-Lactic Acid Increases Collagen Gene Expression and Synthesis in Cultured Dermal Fibroblast (Hs68) Through the p38 MAPK Pathway

No abstract available.

An Anthropometric Study in Korean Humerus / 체질인류학회지

There were few studies about anatomic characteristics in Korean humerus recently. In addition, there was no comparison between Westerner (European and American) and Korean in anatomic characteristics of humerus. The aims of this paper are therefore to investigate anatomic characteristics in Korean humerus and to compare them with those of Westerner humerus. The seventy-two humerus (male : 66, female : 6) were scanned by computed tomography and three dimensional (3D) models of humerus were then reconstructed from acquired cross-section images. The twenty-one anatomic characteristics of the humerus were analyzed and were measured for each humerus. From the results, humeral head vertical diameter in the present study was generally bigger than that in the previous study (p0.05). Humeral head inclination angle, greater tuberosity lateral offset distance, humeral head height in Korean were generally bigger than those in Westerner (p<0.05). This study may contribute to develop an optimal implants and prostheses for the treatment of humerus fractures of Koran.

Airway Remodeling in Mice with Experimentally Induced Airway Allergy

BACKGROUND AND OBJECTIVES: Allergic rhinitis and asthma display many similarities in their epithelial and inflammatory responses to allergens. However, one notable difference is that disruption and desquamation of the epithelium is a characteristic feature of asthma, whereas, in allergic rhinitis, the epithelium is intact. Airway remodeling is a well-recognized feature among patients with chronic asthma but not in allergic rhinitis. The purpose of this study is to investigate the airway remodeling in mice with experimentally induced airway allergy. SUBJECTS AND METHOD: Male BALB/c mice were systemically sensitized with ovalbumin mixed with aluminum hydroxide gel solution and were challenged with aerosols of ovalbumin. Then, the mice were chronically exposed to aerosols of ovalbumin for 5 weeks to 10 weeks. After the last exposure, bronchoalveolar lavage fluid (BALF) and nasal lavage fluid (NLF) were collected. Next, the number of inflammatory cells and the concentrations of IL-5, IL-13, TGF-beta and IFN-gamma in BALF and NLF were measured. Finally, nasal cavity and lung specimen were obtained to evaluate the subepithelial fibrosis by trichrome stain and the expression of MMP-9 and TIMP-1 by immunohistochemical stain. RESULTS: The concentrations of IL-5, IL-13, TGF-beta within the BALF & NLF were found to have significantly increased in the 10-week exposed group compared with the control group. The expression of MMP-9, TIMP-1 and subepithelial fibrosis in the lung tissue were also found to have significantly increased in the 10-week exposed group comparative to that of the control group. But the expression of MMP-9, TIMP-1 and subepithelial fibrosis in the nasal mucosa were not prominent in the 10-week exposed group compared with the control group. CONCLUSION: The results suggest that airway remodeling may be induced by repeated allergen exposure in allergic rhinitis but the structural changes of the nasal mucosa by remodeling process are less prominent compared with the lung tissue.

Effect of Whole Body Vibration on Trabecular Bone in OVX Rats / 체질인류학회지

Previous studies showed that whole body vibration could prevent bone resorption and stimulate new bone formation. The aim of this study is to detect and track effect of whole body vibration for osteoporotic bone of OVX rats. 12 Female rats were used and allocated into 5 group, CON, SHAM, WBV 17, WBV 30 and WBV 45. Rats except SHAM group were ovariectomised to induce osteoporosis. Rats in WBV groups were stimulated whole body vibration at magnitude of 1 mm(peak-peak) and frequency 17 Hz, 30 Hz and 45 Hz, repectively, for 8 weeks (20 min, 5 days/week). The 4th lumbar in rats were scanned at a resolution of 35 micrometer at baseline, before stimulation, and 8 weeks by In-vivo Micro-CT. To detect and track changes of morphological characteristics in lumbar trabecuar bone of rats, structural parameters were measured and calculated from acquiring images. In the results, changes of structural characteristics of WBV group were smaller than those of CON group. Loss of quantity of trabecular bone in WBV 45 was the least. In contrast, that in WBV 17 was the biggest. These results showed that reasonable whole body vibration beneficially affected osteoporotic bones. In addition to, whole body vibration was likely to be substituted partly for drug treatment.

Sclerotherapy of Ranula with Intracystic Injection of OK-432 / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES : Although surgery is the first choice of therapy for ranula, sometimes complete excision is very difficult. Therefore, nonsurgical therapies with less associated morbidity have been required for the treatment of ranula. This study examined the effectiveness of intracystic injection of OK-432 for treatment of ranula. SUBJECTS AND METHOD : Total 32 patients with ranula (24, intraoral type ; 8, plunging type) were treated with OK-432 sclerotherapy. Aspirated mucus of ranula was replaced with an equal volume of OK-432 solution of 0.01 mg/mL. The size of ranula was compared before and after sclerotherapy. RESULTS : Twenty five of 32 patients (78%) showed a complete response after sclerotherapy : higher in plunging ranula (88%) than in intraoral ranula (75%). Rupture of ranula developed in 8 of 25 patients (32%) with intraoral ranula within a few days after injection. Recurrence occurred in 3 patients during follow-up period of median 12 months (range 9-22 months) after last injection. There were no major side effects, scarring, or increased morbidity to surgery of the OK-432 injected lesions. CONCLUSION : The intracystic injection of OK-432 is highly effective as a primary treatment modality of ranula.

A Case of Extramedullary Plasmacytoma of the Hypopharynx / 대한이비인후과학회지

Plasmacytoma is a rare malignancy characterized by a monoclonal proliferation of plasma cells, and is generally classified into a solitary plasmacytoma of bone and extramedullary plasmacytoma. Extramedullary plasmacytoma of the head and neck usually involves submucosal tissues in the nasopharynx and paranasal sinuses. The hypopharyneal involvement of the tumor, however, is very uncommon. We report a case of hypopharyngeal plasmacytoma treated by chemoradiation therapy with a review of literature.