Autonomous Nervous System Activity in Women with Detrusor Overactivity

PURPOSE: To identify autonomic dysfunction among patients with urinary incontinence (UI) with or without detrusor overactivity (DO), we measured and compared heart rate variability (HRV) in these groups. MATERIALS AND METHODS: We studied HRV in 12 female UI patients with DO (mean age, 57.3+/-11.0 years) and 53 female UI patients without DO (mean age, 56.8+/-9.8 years). HRV parameters were measured by SA-3000P(R). Heart rates, the time domain index, and the frequency domain index were compared. To compare time domain indexes, we used the standard deviation of the N-N interval (SDNN), the square root of the mean squared differences of successive N-N intervals (RMSSD), and the frequency domain indexes total power (TP), very low frequency (VLF), low frequency (LF), high frequency (HF), and the low-frequency/high-frequency ratio (LF/HF ratio). RESULTS: RMSSD values were lower in UI patients with DO than in those without DO, but the values of SDNN and HR showed no significant difference. Whereas the values of LF and HF were lower in UI patients with DO than in those without DO, the LF/HF ratio was higher. TP and VLF were not significantly different. CONCLUSIONS: RMSSD, HF, and LF were lower in DO patients than in controls without DO, but the LF/HF ratio was higher. This suggests that both sympathetic and parasympathetic activity is attenuated in DO, but the autonomic imbalance is higher.

Basal Cell Carcinoma of the Prostate

Basal cell carcinoma (BCC) of the prostate, a rare variant of prostate cancer, is derived from the basal cells of prostatic ducts and acini. BCC generally occurs in elderly men with obstructive voiding symptoms and levels of serum prostate-specific antigen within the normal range. In most cases, diagnosis is made through transurethral resection or simple enucleation. Most cases are indolent, but local recurrence and metastasis have been reported in a few cases. Thus, radical surgery and long-term follow-up are recommended. We report a case of a 54-year-old man who underwent radical retropubic prostatectomy after being diagnosed with BCC during a transurethral resection performed for lower urinary tract symptoms. The patient has remained free of disease for 4 months after surgery.

Secondary Polycythemia Caused by Giant Hydronephrosis due to Ureteropelvic Junction Obstruction / 대한비뇨기과학회지

Secondary polycythemia is a condition for which the red blood cell count is increased due to the physiologic response to hypoxia, autonomous erythropoietin production or deliberate erythropoietin administration. Hydronephrosis and postrenal obstruction have rarely been reported as the causes of secondary polycythemia. We report here on a case of a 30-year- old man with secondary polycythemia that was caused by giant hydronephrosis due to ureteropelvic junction obstruction, and this patient was successfully treated by nephrectomy.