RESUMEN
Like all other medical biology tests, the one of medical virology start by the pre-analytical phase, which is a critical step and difficult to manage. It covers the medical prescription with the gathering of the relevant clinical and epidemiological data, the carrying out of the sampling, according to particular modalities, its transport and its storage up to the analysis site. To ensure the accuracy of results, these steps should be in accordance with regulatory requirements, especially according to the universal recognized standards. Among them, the guidance of good practice of analyzes which is the only mandatory reference, opposable to any medical laboratory and other referential taken as voluntary quality approach, for which standard of international accreditation ISO 15189, specific to medical laboratories and which combines requirements regarding quality management and technical requirements