"Effect of organophosphorus insecticides on pregnant rabbits"

The effect of chronic maternal exposure to the organophosphorus insecticide [Tamaron, Bayer], throughout gestation, was studied in 20 pregnant Buscat rabbits and was compared with 10 pregnant controls. A significant reduction in the litter size and in the foetal birth weight was observed in Tamaron-exposed animals. In pregnant rabbits exposed to the insecticide, 10% of the mothers and 9% of their foetuses showed pathologic changes in the liver in the form of zonal necrosis, associated fatty changes and lymphocytic infiltration