Trombose arterial em leucemia promielocítica aguda: [carta ao editor] / Arterial thrombosis in acute promyelocytic leukemia: [letter to the editor]

Acute promyeloclocytic leukemia can present coagulopathies which are frequently very serious due to hemorrhagic conditions. Treatment using anthracyclines and retinoids provide a good response. The development of arterial thrombosis is uncommon. In this work a 56-year-old male patient with acute arterial insufficiency was evaluated. This patient was immediately submitted to thromboembolectomy with the removal of a white thrombus. Postoperative tests showed acute promyelocytic leukemia with transposition (15;17) Treatment with ATRA and Idarubicin chemotherapy was initiated with the patients's response being satisfactory. Currently, the patient is incomplete remission and a recent cytogenetics test does not show the t(15;17).

Porfiria intermitente aguda / Acute intermittent porphyria

Os autores reportam um caso de porfiria aguda intermitente em paciente do sexo feminino, com 24 anos de idade. Revisam os principais aspectos clínicos e terapêuticos relacionados a esta patologia tão complexa