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1.
Artículo en Inglés | IMSEAR | ID: sea-151547

RESUMEN

Polar constituents of Kotschya uguenensis Verdc. (Fabaceae) do not exhibit acute toxicity but cause growth disruption of Anopheles gambiae s.s. Gile (Diptera: Culicidae) larvae with eventual death. Time-course larvicidal effects of powders of root and stem barks and their crude methanol extracts in form of emulsions were compared in the laboratory and in artificial semi-field ponds. Kotschya uguenensis powders of root and stem barks and emulsions of their crude methanol extracts were assayed against An. gambiae s.s according to protocols of WHO 1996 & 2005. All formulations were equally effective under laboratory conditions giving 100% larval mortality within three days at a dose of 50 μg/ml of the extracts or concentrations of powders corresponding to the same level of extractable material. Under semi-field conditions, suspensions of the powder materials appeared to perform better than emulsions of methanol extracts. Time taken to give 80% mortality (LT80) of larvae and pupa at 0.1% w/v was 6.06 days for powders of root bark and 5.60 days for powders of stem bark. The LT80 for the root bark extract at 200 μg/ml was 8.28 days while that for the stem bark methanol extract was 12.47 days. No residual effects of the test materials on the larvae or pupae were evident in semi-field ponds 14 days after the reintroduction of the test materials. Our results suggest that, for the control of anophelines in the field, a weekly application of appropriate amounts of powders of K. uguenensis may be effective.

3.
Tanzan. j. of health research ; 10(1): 47-50, 2008.
Artículo en Inglés | AIM | ID: biblio-1272539

RESUMEN

Long chain aliphatic methyl ketone series of C7-C15 were tested for repellency activity against the malaria transmitting mosquito Anopheles gambiae s.s. All methyl ketones produced a dose dependent (P0.001) repellency response with 2-tridecanone giving comparable protection efficacy to DEET at 10 and 1concentrations. Aliphatic methyl ketones of C7-C10 had lower activity than those of C11-C15. However; within this range compounds with odd carbon atoms (2-undecanone; 2-tridecanone and 2-pentadecanone) were more effective than compounds with even carbon atoms (2-decanone and 2- dodecanone). Comparable repellency activity of 2-tridecanone to DEET show that; it may save as Anopheles gambiae s.s. mosquito repellent


Asunto(s)
Anopheles , Culicidae , Ácidos Grasos , Repelentes de Insectos , Cetonas
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