Colpocephaly, a wide clinical spectrum for one cephalic disorder: three new cases from Kuwait

Colpocephaly is an abnormal enlargement of the occipital horns of both lateral ventricles; it is also described as persistence of the fetal configuration of the lateral ventricles. Since it was first described, Colpocephaly has been found in association with several abnormalities of the brain. The spectrum of clinical presentation is wide, including mainly various degrees of mental retardation, seizures, and motor and visual abnormalities. Approximately 50 cases have been described in children. Herein we report three new cases of Colpocephaly. One of the cases was associated with CHARGE syndrome. To the best of our knowledge, this is the first publication to report such an association