Association deep veinous thrombosis with pulmonary tuberculosis

Thromboembolic complications associated with infection by Mycobacte-rium tuberculosis have been reported in the literature that occurred in 1.5-3.4% of TB infection, which is a risk factor for deep vein thrombosis [DVT] related to the hypercoagulable state secondary to the inflammatory state. We report in this study the pathophysiological, therapeutic, epidemiological, and clinical aspects, of this association. This is a retrospective study done in our department between January 2010 and May 2013. It is about 30 cases of confirmed pulmonary tuberculosis associated with deep vein thrombosis. It is about 21 men and 9 women. Pulmonary tuberculosis was confirmed by the presence of acidoalcoolo-resistant bacillus on the sputum on a direct examination of 25 cases and bronchial aspiration in 5 cases. All patients had extensive radiological lesions. Phlebitis occurred within a mean of 17 days after the diagnosis of tuberculosis. It was confirmed by venous doppler deep ultrasound of inferior membres. All patients received anti-tuberculosis drugs in association with anticoagulant treatment. Etiologic investigations showed positive anti-phospholipid antibodies in one case, and decrease in C and S proteins in 2 patients in which phlebitis was complicated by arterial pulmonary embolism. We had difficulties in controlling prothrombin level in 9 cases and we prescribed low molecular weight heparin for 6 months in two cases. Thromboembolic disease is diagnosed systematically in the TB patients because of the risk of this complication particularly in extensive and severe forms. Prophylactic anticoagulation finds its indications in these forms

[Features of asthma by age]

It is a problem of public health, its prevalence is estimated at 300 millions people around the world, its clinical features diagnostic and therapeutic are very heterogeneous with age, then constitute a difficult task. This is a retrospective comparative study of 81 asthmatics profile divided into 2G + and G2: those over 65 years [GI] subjects under 65 years [G2]. The female is found in both groups, the average age was 69 ans +/- 14 versus 21 years +/- 10 in 1 and 2. In the personal history, it was noted that in patients under age 65 [group 2] there was more of rhinitis and dermatitis, but less of conjunctivitis and this statistically significant [p