RESUMEN
Health care associated infections (nosocomial) are responsible for significant morbidity and mortality among neonatal intensive care patients. The purpose of the study was to assess the effectiveness of Self instructional module in the prevention of nosocomial infection. The study also aimed at improving the knowledge of staff nurses regarding prevention of nosocomial infection. An evaluative approach with one group pre-test post-test design was used in the study.</p> <p>The result of the study showed that in the pre-test knowledge assessment, the mean percentage of response was 50.73% with mean and SD of 15.223 ± 2.5, which was increased to 92.83% with mean and SD of 27.85± 1.20 in the post-test. The results showed a significant difference suggesting that the self instructional module was effective in increasing the knowledge of staff nurses regarding prevention of nosocomial infection (t =26.82, p < 0.05).