Levels of Liver Markers in Textile Processing and Dyeing Industry Workers

Background: The textile dyeing industries has been condemned as being one of the world’s most offenders in terms of pollution. The workers from textile processing and dyeing industry are exposed to various processing chemicals, dyes and different pollutant for long term which may causing hazardous effects on various organs like particularly lung, liver, kidney have become important issue and less data available which explain the effects of these chemicals on biochemical parameters. Aim and Objectives: The aim of this study is to estimate the levels of Liver function markers in textile processing and dyeing industry and healthy controls. Materials & Methods: In this study, 95 subjects working in textile processing and dyeing industry more than 5 years and 95 healthy controls of both gender matching in age and sex were included. The analysis of biochemical parameters was done by using standard grade reagents and chemicals. Serum Bilirubin, Serum Glutamate Oxaloacetate Transaminase (SGOT/AST), Serum Glutamate Pyruvate Transaminase (SGPT/ALT), Alkaline Phosphatase, Serum Protein, Albumin, were assayed by autoanalyzer using diagnostic reagent kit. Results: In the present study Mean of serum bilirubin, SGOT, serum SGPT and alkaline phosphatase is more in Textile processing and dyeing  industry workers than controls. There was no significant change in mean difference of serum proteins, serum albumin and serum globulin (P > 0.05) but highly significant change seen in serum albumin (P = 000) as compared to control. Conclusion: Significant changes were observed for various parameters like serum bilirubin, SGOT, SGPT, alkaline phosphatase, serum proteins are associated with the increased risk of dysfunction of the liver among the textile processing and dyeing industry workers. Increased awareness and early diagnosis of the exposure to toxic substances in textile processing and dyeing industries are essential for performing prompt management, improving clinical outcomes.

Motivation of 1st MBBS Student’s by Active Learning with the Help of Poster Presentation Competition.

Background: All the metabolic pathways, reactions, regulations… Biochemistry seems to be very difficult for 1stMBBS students. Consequently most advanced topics, without a strong basis, difficult to learn, understand, remember and recall. Hence there is no motivation to go ahead for subject studies and leads to difficulty in correlating the knowledge of Biochemistry with clinical conditions. Aims & objectives: i)To improve the 1stMBBS student’s learning process by active participation in poster presentation competition. ii) The students should be able to study the Biochemistry actively, interestingly. Material & Methods: From 150 students, 30 groups each with 5; were formed. The topics selected for the poster presentation competition were having clinical application. Pre-test viva was conducted before, and post-test after the poster presentation. Posters were assessed, by the subject expert and 2 senior teachers. Three best posters were awarded. Results: Improvement in performance of students in post-test (Mean6.993 ± S.D. 1.358) after the poster presentation was highly significant than the pretest poster presentation was highly significant than the pre-test (Mean4.779± S.D. 1.447) (p<o. 00). Group discussion allows student to recognize meanings, express themselves in the language of the subject. The students gain a degree of self-direction & independence in their studies. Conclusion: Poster presentation proved that, it is a useful tool for the motivation of 1st MBBS biochemistry students for studies;& helpful to prepare students to satisfy their clinical responsibilities. Take Home Message: Such type of motivation when used for all 3 basic subjects of MBBS will be helpful to build the basics of the student.