RESUMEN
For new antifungal antibiotics from actinomycetes, a strain of Streptomyces GS 1322 was isolated from a sample of garden soil. The strain was found to possess antagonistic activity against four fungi i.e., Candida albicans, Aspergillus niger, Microsporum gypseum and Trichophyton sp. The strain was identified as Streptomyces sampsonii and the antifungal compound produced by it was found to be the heptaene group of polyene antibiotics.
Asunto(s)
Antibiosis , Antifúngicos/biosíntesis , Aspergillus niger/crecimiento & desarrollo , Candida albicans/crecimiento & desarrollo , ADN Ribosómico/genética , Microsporum/crecimiento & desarrollo , ARN Ribosómico 16S/genética , Microbiología del Suelo , Espectrofotometría Ultravioleta , Streptomyces/química , Trichophyton/crecimiento & desarrolloRESUMEN
A strain of Streptomyces purpeofuscus CM 1261 isolated from a sample of compost collected locally was found to possess strong antagonistic activity against 4 human pathogenic fungi i.e., Candida albicans, Aspergillus niger, Microsporum gypseum and Trichophyton sp. The active antifungal compound produced by it was found to be a heptaene group of polyene antifungal antibiotic.
Asunto(s)
Antifúngicos/aislamiento & purificación , Aspergillus niger/efectos de los fármacos , Candida albicans/efectos de los fármacos , Pruebas de Sensibilidad Microbiana , Microsporum/efectos de los fármacos , Hongos Mitospóricos/efectos de los fármacos , Polienos , Streptomyces/metabolismo , Trichophyton/efectos de los fármacosRESUMEN
Seventeen strains of actinomycetes antagonistic to yeast and moulds have been tested for their ability to produce amylase, lipase, gelatinase and caseinase using solid media containing starch, Tween-20, gelatin and skimmed milk, respectively, Enzyme producing potential of test strains is expressed in ternis of relative enzyme activity (REA). Actinomycetes strain Streptomyces somaliensis GS 1242 and Streptomyces sampsonii GS 1322 showed higher amylase production (REA 6.5) while maximum lipase activity was noted in Streptomyces strain SAP 1089 (REA 7.0). Gelatinase activity was noted higher is S. sampsonii GS 1322 (REA 9.6) and S. somaliensis GS 1242 (REA 8.8). Enzyme producing potential of these strains has been discussed in terms of their industrial significance.