RESUMEN
Objective: To detect the prevalence of physical co-morbidities according to International Classification of Diseases[ICD-10] among patients with Depressive disorder
Design: Descriptive cross sectional study
Setting: Psychiatric consultation clinic of JPMC Karachi
Methods: Patients of either gender and age >18 years were consecutively selected after informed consent, Ethical issues were addressed according to Institutional Review Board [IRB], JPMC, Karachi. Patients with psychotic symptoms, personality disorders, dementia, and history of substance use were excluded. ICD-10 criteria, beside complete history, physical examination and lab investigations were used to confirm the diagnosis of depression and physical co-morbid. Prescribed questionnaire was used to collect the data and analyzed in SPSS version-17. Descriptive statistics were calculated for age, gender, marital status, education, socioeconomic status and co-morbidity
Results: Total 100 cases fulfilled the inclusion criteria. Their Mean +/-SD age was 32.7 +/-16.7 years. Both genders were equally vulnerable, [50% each]. Fifty three percent had moderate, 31% mild and 16% had severe depressive disorder. Hypertension was the most common [18%] in male patients and sinusitis was the most common [28%] in female patients with depression. Other co-morbidities included Diabetes Mellitus, Epilepsy, Migraine, HCV, Anemia, Chronic Kidney Disease [CKD], Urinary Tract Infection [UTI] and Menopausal syndrome [in women], Obesity, Asthma and Facial pain
Conclusion: Physical co-morbidities are prevalent among patients with depressive disorder. Presence of physical co-morbid may decreases the chances of treatment compliance, increases risk of treatment failure, relapse of depression, worse prognosis and elevated the treatment cost. Early detection and simultaneous management of these co-morbid with depression are suggested