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1.
Korean Journal of Family Medicine ; : 143-151, 2014.
Artículo en Inglés | WPRIM | ID: wpr-62969

RESUMEN

BACKGROUND: Colonic neoplasm is associated with western diet intake and physical inactivity. These life styles are also risk factors for dyslipidemia and metabolic syndrome. The aim of this study was to evaluate the association between dyslipidemia and the prevalence of colon polyps including colon adenoma as a precancerous lesion of colonic neoplasms. METHODS: We selected subjects undergoing a colonoscopy for health screening at the Health Promotion Center of Eulji General Hospital from January 2006 to June 2010. Subjects with histories of cancers, dyslipidemia treatment, and other intestinal diseases like Crohn's disease and ulcerative colitis were excluded. The total numbers of subjects included in the study was 605. Chi-square test and t-test and were used for the analysis. Additionally we used multivariate logistic regression to adjust for sex, age, smoking, drinking, and other risk factors. RESULTS: The prevalence of colon polyps was 48.70% and 28.05% in males and females, respectively. When adjusting for variables that included age, body mass index, hypertension, diabetes mellitus, smoking, drinking, and exercise, dyslipidemia was not significantly associated with the prevalence of colon polyps. However upon analyzing adenomatous colon polyps in men, dyslipidemias due to triglycerides and high density lipoproteins were significant factors (odds ratio [OR], 2.13; confidence interval [CI], 1.14 to 3.98; OR, 2.24; CI, 1.15 to 4.34, respectively). CONCLUSION: Dyslipidemia was not a significant factor in the prevalence of colon polyps. However it had a significant association with the prevalence of adenomatous colon polyps in men.


Asunto(s)
Femenino , Humanos , Masculino , Adenoma , Índice de Masa Corporal , Colitis Ulcerosa , Colon , Neoplasias del Colon , Pólipos del Colon , Colonoscopía , Enfermedad de Crohn , Diabetes Mellitus , Dieta , Ingestión de Líquidos , Dislipidemias , Promoción de la Salud , Hospitales Generales , Hipertensión , Enfermedades Intestinales , Estilo de Vida , Lipoproteínas HDL , Modelos Logísticos , Tamizaje Masivo , Pólipos , Prevalencia , Factores de Riesgo , Humo , Fumar , Triglicéridos
2.
Korean Journal of Family Medicine ; : 70-78, 2012.
Artículo en Inglés | WPRIM | ID: wpr-162468

RESUMEN

BACKGROUND: Impaired lung function is associated with mortality rate from cardiovascular and all other death causes. There were previous studies on the relationship between lung function impairment and metabolic syndrome, but they are insufficient. This study was conducted on Koreans to analyze each component of metabolic syndrome as well as its variability between sexes. METHODS: 1,370 subjects underwent a health examination at the Eulji General Hospital Health Center. We examined the association between lung function measurement (forced expiratory volume for 1 second [FEV1], forced vital capacity [FVC], FEV1/FVC) and metabolic syndrome using Student t-test, Pearson partial correlation coefficient, and analysis of covariance for statistical analysis, and we adopted metabolic syndrome defined by American Heart Association/National Heart, Lung, and Blood Institute in Asia. RESULTS: Men with metabolic syndrome tended to experience lung function impairment. In terms of association to each metabolic syndrome component, metabolic syndrome components in men were associated with pulmonary function impairment and the more metabolic syndrome diagnostic criteria factors the patients had, the more severe their pulmonary function tended to decline. In women, waist circumference, triglyceride and high-density lipoprotein cholesterol were associated with pulmonary function change. CONCLUSION: In men, all metabolic syndrome components were associated with pulmonary function impairment, and the more metabolic syndrome components men had, the more severe their pulmonary functions decline. In women, components of metabolic syndrome were not associated with pulmonary function impairment.


Asunto(s)
Femenino , Humanos , Masculino , Causas de Muerte , Colesterol , Volumen Espiratorio Forzado , Corazón , Hospitales Generales , Lipoproteínas , Pulmón , Obesidad Abdominal , Capacidad Vital , Circunferencia de la Cintura
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