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Indian J Exp Biol ; 2005 Sep; 43(9): 773-81
Artículo en Inglés | IMSEAR | ID: sea-60596

RESUMEN

Oral administration of cadmium (6mg/kg body weight/day) as cadmium chloride (CdCl2) for 30 days resulted in a significant increase in thiobarbituric acid reactive substances (TBARS) level and a decrease in the levels of copper, zinc, iron, selenium, glutathione, superoxide dismutase, catalase, glutathione peroxidase when compared to normal control. Administration of either Liv-52 alone or in combination with spirulina produced a well pronounced protective effect in respect to these parameters in cadmium intoxicated rats. The protective effect of spirulina and Liv-52 in respect to biochemical changes were also confirmed by histopathological study in the liver and kidney sections.


Asunto(s)
Animales , Antioxidantes/metabolismo , Depresores del Apetito/farmacología , Proteínas Bacterianas/farmacología , Cadmio/toxicidad , Cloruro de Cadmio/toxicidad , Catalasa/sangre , Cobre/sangre , Combinación de Medicamentos , Glutatión/sangre , Glutatión Peroxidasa/sangre , Hierro/sangre , Riñón/metabolismo , Hígado/metabolismo , Masculino , Extractos Vegetales/farmacología , Ratas , Ratas Wistar , Selenio/sangre , Spirulina , Superóxido Dismutasa/sangre , Sustancias Reactivas al Ácido Tiobarbitúrico/metabolismo , Zinc/sangre
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