RESUMEN
<p><b>OBJECTIVES</b>To study the effect of antisperm antibody(AsAb) on human sperm acrosin activity.</p><p><b>METHODS</b>AsAb and sperm acrosin activity were measured and analyzed in 3,432 infertile men and 65 fertile volunteers.</p><p><b>RESULTS</b>AsAb positive rate was 10.20% in 3,432 case of male infertility, and 9.37% in 2,882 infertile males who received tests of sperm acrosin activity. Acrosin activity of infertility cases were lower than those of fertile cases(P < 0.001). The comparison between AsAb positive group and AsAb negative group infertility cases showed no significant differences of acrosin activity (P > 0.05). Between normal acrosin activity group and abnormal acrosin activity group, there was no significant difference of AsAb positive rate (P > 0.05).</p><p><b>CONCLUSIONS</b>Antisperm antibody could not affect acrosin activity.</p>