RESUMEN
Purpose@#The study investigated the effects of a single bout of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on blood glucose homeostasis and exosome levels in young healthy adults. @*Methods@#A total of 20 healthy young people aged 20 to 30 years were voluntarily recruited from our local community. The subjects were randomly assigned to either HIIT or MICT. @*Results@#The analyses of variance with repeated measures showed that HIIT resulted in a significant treatment (before vs. after HIIT)×time (0, 30, 60, 90, and 120 minutes during oral glucose tolerance tests) interaction (F (1,9) =5.623, p=0.028) on blood glucose concentrations. HIIT resulted in significant decreases in blood glucose levels at 90 minutes (p＜ 0.05) and 120 minutes (p＜ 0.05). MICT did not result in any significant treatment×time interaction on blood glucose concentrations. Neither HIIT nor MICT resulted in any significant treatment×time interaction on blood insulin concentrations. Finally, there was a significant treatment×time interaction (F (1,19) =11.815, p＜ 0.001) in circulating exosome levels. HIIT resulted in a significant increase in exosome levels, whereas MICT did not. @*Conclusion@#In conclusion, the current findings suggest that HIIT would be a better strategy for improving glucose homeostasis than MICT. Yet, the underlying mechanism(s) remain to be unveiled in a future study.