High glucose stimulates the expression of transforming growth factor-β1 and fibronectin via SREBP-1 in HKC cells / 中华内分泌代谢杂志

significantly increased (all P < 0.01). Following SREBP-1 was down-regulated by siRNA, high glucose-stimulated TGF-β1 and FN protein expressions were decreased by 17.9% and 24.6% ,respectively(all P<0.01).