RESUMEN
AIM: To investigate quantitatively the tubulin expression of basal cells in patients with Alzheimer's disease(AD) and vascular dementia(VD) and evaluate its significance in diagnosing Alzheimer's disease. METHODS: ?-tubulin of basal cells was examined using LSAB immunohistochemical technique, and analyzed qualitatively and quantitatively by image analyzer. RESULTS: The integrated absorbance (I A ,261.43?25.21) and the average absorbance (A A ,1.89?0.14) in the AD group were significantly higher than those (I A ,120.55?19.71 and A A , 0.85?0.14, respectively)in the VD group ( P
RESUMEN
Objective: To study the relation among cognitive dysfunction, depression, and location of brain lesion in patients with their first stroke Method: Sixty-two patients with their first episode of single loci stroke demonstrated by CT scan were tested with WAIS-RC, HAMD and SSS Results: Final Intelligence Quotient (FIQ), Verbal Intelligence Quotient (VIQ) and Verbal score of WAIS-RC in patients with anterior lesions were significantly lower than those in patients with posterior lesions (P0 05) Multiple step-regression showed that depression, age and education had influence on IQ of patients Conclusion: Patients with anterior stroke has more cognitive dysfunction
RESUMEN
Objective:To do intelligence test in neurotics.Method:30 neurotics were tested by WAIS-RC.Results:The sub-score of digit span in neurotics was lower than norm(p
RESUMEN
Objective: To confirm the effectiveness of fluoxetine in treatment of depression associated with apparent life events Method: Sixty-two depressive patients who had a total score of the Life Event Scale of more than 30 were treated with fluoxetine for 6 weeks, diazepam was added if necessary CGI, HAMD and HAMA were used to assess the result Result: At the endpoint, the total score of HAMD decreased from 23?4 at baseline to 10?6, the total score of HAMA was also decreased significantly (23?5 to 10?6) At the meantime, the HAMD sleep factor and CGI severity score were also decreased significantly All above measurements showed improvement at the first week of treatment The adverse effects were mild, with lose of appetite, dry mouth and nausea as the most frequently seen, which had no influence on treatment process Conclusion: Fluoxetine plus diazepam is effective in depressive patients with apparent life events with quick response and mild adverse effects