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Korean Journal of Medicine ; : 425-431, 2004.
Artículo en Coreano | WPRIM | ID: wpr-99260

RESUMEN

POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal M protein, and skin lesion) is a rare multisystemic disease of unknown cause with varying clinical manifestations. Amyloidosis-associated POEMS Syndrome is also rare condition. We experienced a 63-year-old female who had been suffered from edema and tingling sensation of low extremities. She also had a marked demyelination, axonal degeneration and regeneration of the nerve, hypoaldosteronism, hyperprolactinemia, decreased sexual hormone, monoclonal gammopathy (IgG lambda type), skin change and ascites. The renal biopsy revealed homogenous mesangial widening with a few cell nuclei at the glomerular capillary, and it showed positive apple-green birefringence in Congo-red stain. It's the first report that shows the deposition of amyloid in patients with POEMS syndrome in Korea. Edema and M-spike were improved by use of prednisolone, melphalan, fludrocortisone and colchicine.


Asunto(s)
Femenino , Humanos , Persona de Mediana Edad , Amiloide , Amiloidosis , Ascitis , Axones , Biopsia , Birrefringencia , Capilares , Núcleo Celular , Colchicina , Enfermedades Desmielinizantes , Edema , Extremidades , Fludrocortisona , Hiperprolactinemia , Hipoaldosteronismo , Corea (Geográfico) , Melfalán , Paraproteinemias , Síndrome POEMS , Prednisolona , Regeneración , Sensación , Piel
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