RESUMEN
Objective To observe the clinical efficacy of Shiwei Longdanhua Capsule combined with western medicine on patients with mild acute exacerbation of chronic obstructive pulmonary disease (COPD) with phlegm-heat obstructing lung syndrome. Methods Totally 192 cases of COPD with mild acute exacerbation (phlegm-heat obstructing lung syndrome) were recruited. They were randomly divided into the treatment group (96 cases) and the control group (96 cases). Patients in the control group were treated in line with the regular Western treatment, while patients in the treatment group were additionally treated by Shiwei Longdanhua Capsule. After 10-day treatment, the changes of TCM syndrome score, symptom integral and the lung function before and after treatment were compared. Results After treatment, 14 patients withdrew from the treatment group and 15 patients withdrew from the control group. The total efficiency rate of TCM syndrome was 80.49% (66/82) in the treatment group, while it was 56.79% (46/81) in the control group, with statistical difference between the two groups (P<0.05). The severity and frequency of cough and expectoration of the treatment group were better than the control group (P<0.05). The breathing symptom and pulmonary function of patients in the two groups improved, with similar efficacy. Conclusion The efficiency of Shiwei Longdanhua Capsule combined with Western medicine in the treatment of acute exacerbation of COPD is superior to that of simple Western medicine treatment, especially in terms of relieving cough and expectoration.
RESUMEN
Objective To observe the Clinical effects on Sanao tables combined with Montelukast Tables for cough variant asthma (CVA) (cold beam lung card).Methods Eighty-nine cases of sydrome differentiation (cold beam lung card) complied with CVA diagnostic criteria were randomly divided into treatment group (45 cases,3 cases were lost) and control group(44 cases,4 cases were lost)).The treatment group was given oral San'ao tables combined with Montelukast tables,and the control group was given oral Montelukast tables.The course of treatment were all 14 days.Chinese medical syndrome,cardinal symptom and airway reactivity effects were determined and compared at pretherapy.Results Clinical effects of Chinese medical syndrome (effective rate (90.48％,38/42),cough severity (85.71％,36/42),frequency (90.48％,38/42),cough up phlegm (85.71％,36/42),pharyngeal itching (80.95％,4/42) and aversion to cold (76.19％,32/ 42)) in treatment group were all superior to control group (70.00％ (28/40),62.50％ (25/40),70.00％ (28/ 40),55.00％ (22/40),52.50％ (21/40),25.00％ (10/40)).The differences were statistical significance (x2=14.046,14.046,13.923,23.104,17.729,17.729;P＜0.05 or P＜0.01).Conclusion Clinical effects of San' ao tables combined with Montelukast tables on CVA is superior to Montelukast tables.