RESUMEN
Objective: To evaluate the clinical therapeutic effects of excision of invaded sacrospinous ligament on pelvic cavity pain caused by endometriosis
Methods: Eighty endometriotic patients treated in our hospital from January 2013 to December 2014 were chosen, and divided into a control group and an observation group. Regular operation [i.e. excision of endometriotic nidus and separation of pelvic cavity adhesion] was performed for the control group, while regular operation and sacrospinous ligament excision were conducted for the observation group. Intraoperative and postoperative conditions as well as postoperative pain remission of both groups were compared
Results: For the amount of bleeding during operation, the control group was [120 +/- 5.2] ml, while the observation group was [160 +/- 4.0] ml. For the duration of operation, the control group was [65 +/- 3.4] minutes, while the observation group was [92 +/- 2.6] min [p<0.05], with a significant difference. For the independent urination time after operation, the control group was [32 +/- 8.8] hour, while the observation group was [33 +/- 6.4] hour. For the evacuation time after operation, the control group was [38 +/- 2.6] hour, while the observation group was [39 +/- 3.0] hour [p>0.05], with a significant difference. The postoperative VAS scores of the two groups were significantly lower than those before operation, and the VAS score of the observation group was significantly lower than that of the control group, p<0.05
Conclusion: Sacrospinous ligament excision relieved pain caused by endometriosis, so it may be applicable to the endometriosis patients with sacrospinous ligament infiltration or severe pain
RESUMEN
Objective: To evaluate the therapeutic effects of metformin and clomiphene in combination with lifestyle adjustment on infertility in women with obese polycystic ovarian syndrome [PCOS]
Methods: A total of 101 infertile women with obese PCOS admitted to our hospital from July 2013 to July 2015 were randomly divided into an observation group [n=51] and a control group [n=50]. The control group was treated with metformin plus clomiphene, based on which the observation group was also subjected to lifestyle adjustment. The body weight, body mass index [BMI] and waist-to-hip ratio [WHR] were measured before and after treatment. The changes of reproductive hormones, ovaries and endometrium were detected, and the rates of menstrual recovery, ovulation and pregnancy were observed
Results: The body weight and BMI of the observation group after treatment were significantly lower than those before treatment and of the control group [P<0.05]. There was no significant difference in WHR between the two groups. In the observation group, there were significant differences in LH, T, LH/FSH, FINS and TG levels before and after treatment and from those of the control group after treatment [P<0.05]. Both the left and right ovarian volumes of the observation group after treatment were significantly lower than those before treatment and of the control group after treatment [P<0.05]. The menstrual recovery, ovulation and pregnancy rates of the observation group were significantly higher than those of the control group [P<0.05]
Conclusion: Lifestyle adjustment combined with metformin and clomiphene can improve the reproductive endocrine and lipid metabolism of obese PCOS patients, decrease the volumes of left and right ovaries, and increase the menstrual recovery, ovulation and pregnancy rates