1.
Chinese Journal of Biotechnology
;
(12): 33-43, 2020.
Artículo
en Chino
| WPRIM
| ID: wpr-787690
RESUMEN
Bispecific antibody (BsAbs) are antibodies (Abs) containing two different antigen-binding sites in one molecule. In the last decade, three BsAbs drugs have been approved for therapeutic use. Meanwhile there are a number of BsAbs in preclinical or clinical studies. In this review, we describe BsAb design, discovery, mechanism of action, and the recent research progress in developing BsAbs.